The study of innate immunity and its link to inflammation and host defense encompasses
diverse areas of biology, ranging from genetics and biophysics to signal transduction and …

Short ORFs (sORFs), that is, occurrences of a start and stop codon within 100 codons or
less, can be found in organisms of all domains of life, outnumbering annotated protein …

Translation is pervasive outside of canonical coding regions, occurring in long noncoding
RNAs, canonical untranslated regions and introns,,–, especially in ageing …

Mito-SEPs are small open reading frame-encoded peptides that localize to the mitochondria
to regulate metabolism. Motivated by an intriguing negative association between mito-SEPs …

As a common pathology of many ocular disorders such as diabetic retinopathy and
glaucoma, retinal ischemia/reperfusion (IR) triggers inflammation and microglia activation …

Emerging evidence indicates that a subset of RNA molecules annotated as noncoding
contain short open reading frames that code for small functional proteins called …

Next-generation sequencing (NGS) technologies have greatly expanded the size of the
known transcriptome. Many newly discovered transcripts are classified as long noncoding …

Regulatory non‐coding RNAs (ncRNAs) including small non‐coding RNAs (sRNAs), long
non‐coding RNAs (lncRNAs), and circular RNAs (circRNAs) have gained considerable …

Micropeptides are a recently discovered class of molecules that play vital roles in various
cellular processes, including differentiation, proliferation, and apoptosis. Here, we sought to …

Long non-coding RNAs (lncRNAs) were originally defined as non-coding RNAs (ncRNAs)
which lack protein-coding ability. However, with the emergence of technologies such as …