Cell-based drug delivery systems and their in vivo fate
L Yang, Y Yang, Y Chen, Y Xu, J Peng - Advanced Drug Delivery Reviews, 2022 - Elsevier
Cell-based drug delivery systems (DDSs) have received attention recently because of their
unique biological properties and self-powered functions, such as excellent biocompatibility …
unique biological properties and self-powered functions, such as excellent biocompatibility …
Macrophage-based cell therapies: the long and winding road
In the quest for better medicines, attention is increasingly turning to cell-based therapies.
The rationale is that infused cells can provide a targeted therapy to precisely correct a …
The rationale is that infused cells can provide a targeted therapy to precisely correct a …
Antiretroviral neurotoxicity
K Robertson, J Liner, RB Meeker - Journal of neurovirology, 2012 - Springer
Combination antiretroviral therapy (CART) has proven to effectively suppress systemic HIV
burden, however, poor penetration into the central nervous system (CNS) provides …
burden, however, poor penetration into the central nervous system (CNS) provides …
Use of macrophages to deliver therapeutic and imaging contrast agents to tumors
J Choi, HY Kim, EJ Ju, J Jung, J Park, HK Chung… - Biomaterials, 2012 - Elsevier
Drug targeting to tumors with limited toxicity and enhanced efficacy of drug is one of the
important goals for cancer treatment pharmaceutics. Monocytes/macrophages are able to …
important goals for cancer treatment pharmaceutics. Monocytes/macrophages are able to …
Transformation of tenofovir into stable ProTide nanocrystals with long-acting pharmacokinetic profiles
Abstract Treatment and prevention of human immunodeficiency virus type one (HIV-1)
infection was transformed through widespread use of antiretroviral therapy (ART). However …
infection was transformed through widespread use of antiretroviral therapy (ART). However …
Neurotoxicity in the post-HAART era: caution for the antiretroviral therapeutics
A Shah, MR Gangwani, NS Chaudhari, A Glazyrin… - Neurotoxicity …, 2016 - Springer
Despite the advent of highly active antiretroviral therapy (HAART), HIV-associated
neurological disorders (HAND) remain a major challenge in human immunodeficiency virus …
neurological disorders (HAND) remain a major challenge in human immunodeficiency virus …
Nanomaterials in cancer-therapy drug delivery system
G Zhang, X Zeng, P Li - Journal of biomedical nanotechnology, 2013 - ingentaconnect.com
Nanomaterials can enhance the delivery and treatment efficiency of anti-cancer drugs, and
the mechanisms of the tumorreducing activity of nanomaterials with cancer drug have been …
the mechanisms of the tumorreducing activity of nanomaterials with cancer drug have been …
Antiretroviral solid drug nanoparticles with enhanced oral bioavailability: production, characterization, and in vitro–in vivo correlation
TO McDonald, M Giardiello, P Martin… - Advanced …, 2014 - Wiley Online Library
Nanomedicine strategies have produced many commercial products. However, no orally
dosed HIV nanomedicines are available clinically to patients. Although nanosuspensions of …
dosed HIV nanomedicines are available clinically to patients. Although nanosuspensions of …
Nanoparticle-based drug delivery to improve the efficacy of antiretroviral therapy in the central nervous system
Antiretroviral drug therapy plays a cornerstone role in the treatment of human
immunodeficiency virus (HIV)/acquired immunodeficiency syndrome patients. Despite …
immunodeficiency virus (HIV)/acquired immunodeficiency syndrome patients. Despite …
Cell-mediated transfer of catalase nanoparticles from macrophages to brain endothelial, glial and neuronal cells
MJ Haney, Y Zhao, S Li, SM Higginbotham… - …, 2011 - Taylor & Francis
Background: Our laboratories forged the concept of macrophage delivery of protein
antioxidants to attenuate neuroinflammation and nigrostriatal neurodegeneration in …
antioxidants to attenuate neuroinflammation and nigrostriatal neurodegeneration in …