Chronic obstructive pulmonary disease and the cardiovascular system: vascular repair and regeneration as a therapeutic target

S Karnati, M Seimetz, F Kleefeldt… - Frontiers in …, 2021 - frontiersin.org
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality
worldwide and encompasses chronic bronchitis and emphysema. It has been shown that …

Impaired alveolar re-epithelialization in pulmonary emphysema

CR Lin, K Bahmed, B Kosmider - Cells, 2022 - mdpi.com
Alveolar type II (ATII) cells are progenitors in alveoli and can repair the alveolar epithelium
after injury. They are intertwined with the microenvironment for alveolar epithelial cell …

[HTML][HTML] Gallic acid suppresses inflammation and oxidative stress through modulating Nrf2-HO-1-NF-κB signaling pathways in elastase-induced emphysema in rats

F Sohrabi, M Dianat, M Badavi, M Radan… - … Science and Pollution …, 2021 - Springer
Emphysema is associated with an abnormal airspace enlargement distal to the terminal
bronchioles accompanied by destructive changes in the alveolar walls and chronic …

Retinoic acid: a key regulator of lung development

H Fernandes-Silva, H Araújo-Silva, J Correia-Pinto… - Biomolecules, 2020 - mdpi.com
Retinoic acid (RA) is a key molecular player in embryogenesis and adult tissue
homeostasis. In embryo development, RA plays a crucial role in the formation of different …

All‑trans retinoic acid promotes macrophage phagocytosis and decreases inflammation via inhibiting CD14/TLR4 in acute lung injury

S Li, Y Lei, J Lei, H Li - Molecular medicine reports, 2021 - spandidos-publications.com
Acute lung injury (ALI) is a common clinical emergency and all‑trans retinoic acid (ATRA)
can alleviate organ injury. Therefore, the present study investigated the role of ATRA in ALI …

Heterogeneous cancer‐associated fibroblasts: a new perspective for understanding immunosuppression in pancreatic cancer

Z Zhang, H Zhang, L Shi, D Wang, D Tang - Immunology, 2022 - Wiley Online Library
Immunotherapy has shown promising efficacy in the treatment of a wide range of cancers;
however, it has had little effect on pancreatic cancer. Cancer‐associated fibroblasts (CAFs) …

[HTML][HTML] Ellagic acid ameliorates lung inflammation and heart oxidative stress in elastase-induced emphysema model in rat

Z Mansouri, M Dianat, M Radan, M Badavi - Inflammation, 2020 - Springer
Chronic obstructive pulmonary disease (COPD) is one of the most important factors in the
progress of cardiovascular disease (CVD) which is associated with limited airflow and …

Effects of Vitamin A on Immune Responses and Vitamin A Metabolism in Broiler Chickens Challenged with Necrotic Enteritis

S Guo, L He, Y Zhang, J Niu, C Li, Z Zhang, P Li… - Life, 2023 - mdpi.com
Simple Summary Vitamin A is an anti-inflammatory vitamin and essential for the health of
humans and animals. Necrotic enteritis is an enteric inflammatory disease in poultry caused …

Modulation of inflammation-induced tolerance in cancer

V Rogovskii - Frontiers in Immunology, 2020 - frontiersin.org
Chronic inflammation is widely accepted to be an important cause of tumor formation and
development (1, 2). The primary significance of chronic inflammation in cancer may be in its …

[HTML][HTML] Does gallic acid improve cardiac function by attenuation of oxidative stress and inflammation in an elastase-induced lung injury?

F Sohrabi, M Dianat, M Badavi, M Radan… - Iranian Journal of …, 2020 - ncbi.nlm.nih.gov
Objective (s): Cardiovascular disease has an important role in mortality caused by lung
injury. Emphysema is associated with impaired pulmonary gas exchange efficiency and …