Translational models of arrhythmia mechanisms and susceptibility: success and challenges of modeling human disease

JS Piktel, LD Wilson - Frontiers in Cardiovascular Medicine, 2019 - frontiersin.org
We discuss large animal translational models of arrhythmia susceptibility and sudden
cardiac death, focusing on important considerations when interpreting the data derived …

Low‐level tragus stimulation modulates atrial alternans and fibrillation burden in patients with paroxysmal atrial fibrillation

K Kulkarni, JP Singh, KA Parks… - Journal of the …, 2021 - Am Heart Assoc
Background Low‐level tragus stimulation (LLTS) has been shown to significantly reduce
atrial fibrillation (AF) burden in patients with paroxysmal AF. P‐wave alternans (PWA) is …

Cardiac contractility modulation in patients with heart failure—A review of the literature

G Bazoukis, A Saplaouras, P Efthymiou… - Heart Failure …, 2024 - Springer
Experimental in vivo and in vitro studies showed that electric currents applied during the
absolute refractory period can modulate cardiac contractility. In preclinical studies, cardiac …

ECG segmentation and fiducial point extraction using multi hidden Markov model

M Akhbari, MB Shamsollahi, O Sayadi… - Computers in biology …, 2016 - Elsevier
In this paper, we propose a novel method for extracting fiducial points (FPs) of
electrocardiogram (ECG) signals. We propose the use of multi hidden Markov model …

Design implementation and evaluation of a mobile continuous blood oxygen saturation monitoring system

Q Zhang, D Arney, JM Goldman, EM Isselbacher… - Sensors, 2020 - mdpi.com
Objective: In this study, we built a mobile continuous Blood Oxygen Saturation (SpO2)
monitor, and for the first time, explored key design principles towards daily applications …

ECG denoising and fiducial point extraction using an extended Kalman filtering framework with linear and nonlinear phase observations

M Akhbari, MB Shamsollahi, C Jutten… - Physiological …, 2016 - iopscience.iop.org
In this paper we propose an efficient method for denoising and extracting fiducial point (FP)
of ECG signals. The method is based on a nonlinear dynamic model which uses Gaussian …

Stress influence on real-world driving identified by monitoring heart rate variability and morphologic variability of electrocardiogram signals: the case of intercity roads

S Rostamzadeh, A Abouhossein… - … of occupational safety …, 2024 - Taylor & Francis
Objectives. This study examines which of the heart rate variability (HRV) and morphologic
variability (MV) metrics may have the highest accuracy in different stress detection during …

A novel point-of-care smartphone based system for monitoring the cardiac and respiratory systems

K Sohn, FM Merchant, O Sayadi, D Puppala… - Scientific reports, 2017 - nature.com
Cardio-respiratory monitoring is one of the most demanding areas in the rapidly growing,
mobile-device, based health care delivery. We developed a 12-lead smartphone-based …

Time-warping analysis of the t-wave peak-to-end interval to quantify ventricular repolarization dispersion during ischemia

N Gómez, J Ramírez, JP Martínez… - IEEE Journal of …, 2023 - ieeexplore.ieee.org
Variations in the dispersion of ventricular repolarization can be quantified by T-wave time-
warping based index,. However, the early phase of the T-wave can be affected by ST …

Utility of a smartphone based system (cvrPhone) to predict short-term arrhythmia susceptibility

K Sohn, SP Dalvin, FM Merchant, K Kulkarni, F Sana… - Scientific reports, 2019 - nature.com
Repolarization alternans (RA) has been implicated in the pathogenesis of ventricular
arrhythmias and sudden cardiac death. We developed a 12-lead, blue-tooth/Smart-Phone …