The constructive and destructive impact of autophagy on both genders' reproducibility, a comprehensive review

M Samare-Najaf, A Neisy, A Samareh, D Moghadam… - Autophagy, 2023 - Taylor & Francis
Reproduction is characterized by a series of massive renovations at molecular, cellular, and
tissue levels. Recent studies have strongly tended to reveal the involvement of basic …

Effects of folic acid and folic acid plus zinc supplements on the sperm characteristics and pregnancy outcomes of infertile men: A systematic review and meta-analysis

X Li, Y Zeng, J He, B Luo, X Lu, L Zhu - Heliyon, 2023 - cell.com
Background Folic acid and zinc supplements have been used to treat male infertility, but
their efficacy is still debated. Objective To systematically evaluate the effects of folic acid and …

ROS-induced oxidative stress is a major contributor to sperm cryoinjury

H Shi, QY Li, H Li, HY Wang, CX Fan… - Human …, 2024 - academic.oup.com
STUDY QUESTION What is the mechanism behind cryoinjury in human sperm, particularly
concerning the interplay between reactive oxygen species (ROS) and autophagy, and how …

In Vitro Transcriptional Response of Eimeria tenella to Toltrazuril Reveals That Oxidative Stress and Autophagy Contribute to Its Anticoccidial Effect

L Zhang, H Zhang, S Du, X Song, D Hu - International Journal of …, 2023 - mdpi.com
Intestinal coccidiosis is a common parasitic disease in livestock, caused by the infection of
Eimeria and Cystoisospora parasites, which results in great economic losses to animal …

Adverse effects of single neutrophil extracellular trap-derived components on bovine sperm function

C Moya, R Rivera-Concha, F Pezo, P Uribe, M Schulz… - Animals, 2022 - mdpi.com
Simple Summary Neutrophil extracellular traps (NETs) play a key role in fertilisation by
eliminating microorganisms and entrapping spermatozoa in the female reproductive tract …

The autophagy marker LC3 is processed during the sperm capacitation and the acrosome reaction and translocates to the acrosome where it colocalizes with the …

IM Aparicio, P Rojo-Domínguez… - International journal of …, 2023 - mdpi.com
Despite its importance in somatic cells and during spermatogenesis, little is known about the
role that autophagy may play in ejaculated spermatozoa. Our aim was to investigate whether …

Hypoxia enhances autophagy level of human sperms

J Hu, J Wu, X Liu, Y Zhang, L Mo, L Liu, S Liu, C Ou… - Scientific Reports, 2024 - nature.com
The relationship between oxygen sensing and autophagy in human sperms was explored in
this study. Health semen and asthenozoospermia (astheno) semen were incubated with …

Single-cell insights into mouse testicular toxicity under peripubertal exposure to di (2-ethylhexyl) phthalate

Y Li, Y Tian, M Xu, X Qiu, Z Bao, M Shi… - Toxicological …, 2024 - academic.oup.com
Male fertility depends on normal pubertal development. Di (2-ethylhexyl) phthalate (DEHP)
is a potent antiandrogen chemical, and exposure to DEHP during peripuberty can damage …

[HTML][HTML] Advancements in the ERK1/2 signaling pathway affecting male reproduction

Y Du, X Chi, Y Wang, X Cai, W Zeng, Y Huo… - Frontiers in Bioscience …, 2024 - imrpress.com
Male infertility, age-related changes, and tumors have been increasingly studied in the field
of male reproductive health due to the emergence of environmental stressors, declining …

Sperm freezing damage: the role of regulated cell death

E Hai, B Li, J Zhang, J Zhang - Cell Death Discovery, 2024 - nature.com
Substantial progress in research on sperm cryopreservation has occurred since the
twentieth century, especially focusing on improving sperm freezing procedures and …