Ruthenium (II) polypyridyl complexes form a vast family of molecules characterized by their
finely tuned photochemical and photophysical properties. Their ability to undergo excited …

Effective treatment delivery in photodynamic therapy (PDT) requires coordination of the light
source, the photosensitizer, and the delivery device appropriate to the target tissue. Lasers …

A significant mortality rate is associated with oral cancer, particularly in cases of late-stage
diagnosis. Since the last decades, oral cancer survival rates have only gradually improved …

Photoactivated chemotherapy is an approach where a biologically active compound is
protected against interaction with the cell environment by a light-cleavable protecting group …

The ongoing nanotech revolution has the potential to transform diagnostic and therapeutic
methods. Stimuli-triggered nanotherapies based on remotely activated agents have become …

Multiple clinical studies have shown that interstitial photodynamic therapy (I-PDT) is a
promising modality in the treatment of locally-advanced cancerous tumors. However, the …

Marine alkaloid rigidins are cytotoxic compounds known to kill cancer cells at nanomolar
concentrations by targeting the microtubule network. Here, a rigidin analogue containing a …

This review follows the research, development and clinical applications of the
photosensitizer 5, 10, 15, 20‐tetra (m‐hydroxyphenyl) chlorin (m THPC, temoporfin) in …

Photodynamic therapy (PDT) induces cell death through local light activation of a
photosensitizer (PS) and has been used to treat head and neck cancers. Yet, common PS …

Oral cancer is a global health burden with significantly poor survival, especially when the
diagnosis is at its late stage. Despite advances in current treatment modalities, there has …