Histological fibrosis stage is one of the most important prognostic factors in compensated
and decompensated alcohol-related liver disease (ALD). Morphological assessment of …

Elevated mitochondrial matrix superoxide and/or hydrogen peroxide concentrations drive a
wide range of physiological responses and pathologies. Concentrations of superoxide and …

Hepatocellular carcinoma (HCC) is the seventh most highly prevalent malignant tumor
globally and the second most common cause of mortality. HCC develops with complex …

Glutathione S-transferase Mu 1 (GSTM1) and glutathione S-transferase theta 1 (GSTT1)
enzymes are glutathione-S-transferases with broad significance for susceptibility or …

Alcohol use disorder (AUD) and cirrhosis are key outcomes of excessive alcohol use, and a
genetic influence in these outcomes is increasingly recognized. While 80–90% of heavy …

Background The chronic‐plus‐binge model of ethanol consumption, where chronically (8‐
week) ethanol‐fed mice are gavaged a single dose of ethanol (E8G1), is known to induce …

Background and aims Alcoholic liver disease (ALD) is the leading cause of the liver cirrhosis
related death worldwide. Excessive alcohol consumption resulting enhanced gut …

Background It is unclear whether brief interventions using the combined classification of
alcohol-metabolizing enzymes aldehyde dehydrogenase 2 (ALDH2) and alcohol …

Abstract Background Groundwater Arsenic (As) contamination is a global public health
concern responsible for various health implications and a neglected area of environmental …

Research into the genetic underpinnings of neuropsychiatric illness has occurred at many
levels. As more information accumulates, it appears that many approaches may each offer …