[HTML][HTML] Tumor protein D52 (TPD52) and cancer—oncogene understudy or understudied oncogene?
Abstract The Tumor protein D52 (TPD52) gene was identified nearly 20 years ago through
its overexpression in human cancer, and a substantial body of data now strongly supports …
its overexpression in human cancer, and a substantial body of data now strongly supports …
The tumor protein D52 family: many pieces, many puzzles
Tumor protein D52-like proteins are small coiled-coil motif bearing proteins which are
conserved from lower organisms to human. The founding member of the family, human D52 …
conserved from lower organisms to human. The founding member of the family, human D52 …
PrLZ, a Novel Prostate-Specific and Androgen-Responsive Gene of the TPD52 Family, Amplified in Chromosome 8q21.1 and Overexpressed in Human …
R Wang, J Xu, O Saramäki, T Visakorpi… - Cancer research, 2004 - AACR
We report a previously unrecognized prostate-specific protein, PrLZ (prostate leucine
zipper), a new member of the Tumor Protein D52 (TPD52) family. The gene for PrLZ was …
zipper), a new member of the Tumor Protein D52 (TPD52) family. The gene for PrLZ was …
Tumor protein D52 (TPD52) is overexpressed and a gene amplification target in ovarian cancer
JA Byrne, RL Balleine, MS Fejzo… - … journal of cancer, 2005 - Wiley Online Library
Recurrent chromosome 8q gain in ovarian carcinoma is likely to reflect the existence of
multiple target loci, as the separate gain of chromosome bands 8q21 and 8q24 has been …
multiple target loci, as the separate gain of chromosome bands 8q21 and 8q24 has been …
Altered expression of tumor protein D52 regulates apoptosis and migration of prostate cancer cells
R Ummanni, S Teller, H Junker… - The FEBS …, 2008 - Wiley Online Library
Tumor protein D52 (TPD52) is a protein found to be overexpressed in prostate and breast
cancer due to gene amplification. However, its physiological function remains under …
cancer due to gene amplification. However, its physiological function remains under …
The hD52 (TPD52) gene is a candidate target gene for events resulting in increased 8q21 copy number in human breast carcinoma
RL Balleine, MS Fejzo, P Sathasivam… - Genes …, 2000 - Wiley Online Library
Chromosome band 8q21 is frequently overrepresented in human cancer, but to date no
8q21 target gene has been proposed. The hD52 (TPD52) gene is of potential significance in …
8q21 target gene has been proposed. The hD52 (TPD52) gene is of potential significance in …
Identification of MAL2, a novel member of the mal proteolipid family, though interactions with TPD52-like proteins in the yeast two-hybrid system
SHD Wilson, AM Bailey, CR Nourse, MG Mattei… - Genomics, 2001 - Elsevier
The TPD52 (tumor protein D52)-like proteins are small coiled-coil motif-bearing proteins
which were first identified though their expression in human breast carcinoma. TPD52-like …
which were first identified though their expression in human breast carcinoma. TPD52-like …
Identification of homo-and heteromeric interactions between members of the breast carcinoma-associated D52 protein family using the yeast two-hybrid system
The hD52 gene was originally identified through its elevated expression level in human
breast carcinoma. Cloning of D52 homologues from other species has indicated that D52 …
breast carcinoma. Cloning of D52 homologues from other species has indicated that D52 …
Induction of tumorigenesis and metastasis by the murine orthologue of tumor protein D52
JD Lewis, LA Payton, JG Whitford, JA Byrne… - Molecular cancer …, 2007 - AACR
Expression studies have consistently identified tumor protein D52 (TPD52) overexpression
in tumor cells. Murine TPD52 (mD52) shares 86% identity with the human orthologue. To …
in tumor cells. Murine TPD52 (mD52) shares 86% identity with the human orthologue. To …
Transgenic mouse model for breast cancer: induction of breast cancer in novel oncogene HCCR-2 transgenic mice
J Ko, SM Shin, YM Oh, YS Lee, ZY Ryoo, YH Lee… - Oncogene, 2004 - nature.com
Transgenic mice containing novel oncogene HCCR-2 were generated to analyse the
phenotype and to characterize the role of HCCR-2 in cellular events. Mice transgenic for …
phenotype and to characterize the role of HCCR-2 in cellular events. Mice transgenic for …