The 1, 3, 4‐thiadiazole nucleus is one of the most important and well‐known heterocyclic
nuclei, which is a common and integral feature of a variety of natural products and medicinal …

Chagas disease caused by Trypanosoma cruzi remains an important neglected tropical
disease and a cause of significant morbidity and mortality. No longer confined to endemic …

RESUMO A doença de Chagas é uma condição crônica negligenciada com elevada carga
de morbimortalidade e impacto dos pontos de vista psicológico, social e econômico …

Chagas disease is a neglected chronic condition with a high burden of morbidity and
mortality. It has considerable psychological, social, and economic impacts. The disease …

Post-infectious conditions present major health burdens but remain poorly understood. In
Chagas disease (CD), caused by Trypanosoma cruzi parasites, antiparasitic agents that …

Chagas disease is caused by a parasite, Trypanosoma cruzi, transmitted primarily by a
triatomine insect and affects approximately 8 million people in Latin American countries. The …

Abstract Background The trypanosomatids Leishmania major, Trypanosoma brucei and
Trypanosoma cruzi cause some of the most debilitating diseases of humankind: cutaneous …

Objectives: We sought to investigate whether myocardial delayed enhancement (MDE) by
magnetic resonance imaging (MRI) could quantify myocardial fibrosis (MF) in patients with …

Treatment for Chagas disease with currently available medications is recommended
universally only for acute cases (all ages) and for children up to 14 years old. The World …

Chagas heart disease (CHD) results from infection with the protozoan parasite
Trypanosoma cruzi and is the leading cause of infectious myocarditis worldwide. It poses a …