1, 3, 4‐Thiadiazole and its derivatives: A review on recent progress in biological activities
AK Jain, S Sharma, A Vaidya… - Chemical biology & …, 2013 - Wiley Online Library
The 1, 3, 4‐thiadiazole nucleus is one of the most important and well‐known heterocyclic
nuclei, which is a common and integral feature of a variety of natural products and medicinal …
nuclei, which is a common and integral feature of a variety of natural products and medicinal …
[HTML][HTML] Current understanding of immunity to Trypanosoma cruzi infection and pathogenesis of Chagas disease
Chagas disease caused by Trypanosoma cruzi remains an important neglected tropical
disease and a cause of significant morbidity and mortality. No longer confined to endemic …
disease and a cause of significant morbidity and mortality. No longer confined to endemic …
[HTML][HTML] II Consenso Brasileiro em doença de Chagas, 2015
JCP Dias, AN Ramos Jr, ED Gontijo… - … e Serviços de …, 2016 - SciELO Public Health
RESUMO A doença de Chagas é uma condição crônica negligenciada com elevada carga
de morbimortalidade e impacto dos pontos de vista psicológico, social e econômico …
de morbimortalidade e impacto dos pontos de vista psicológico, social e econômico …
[HTML][HTML] 2 nd Brazilian Consensus on Chagas Disease, 2015
JCP Dias, AN Ramos Jr, ED Gontijo… - Revista da Sociedade …, 2016 - SciELO Brasil
Chagas disease is a neglected chronic condition with a high burden of morbidity and
mortality. It has considerable psychological, social, and economic impacts. The disease …
mortality. It has considerable psychological, social, and economic impacts. The disease …
[HTML][HTML] Localized cardiac small molecule trajectories and persistent chemical sequelae in experimental Chagas disease
Z Liu, R Ulrich vonBargen, AL Kendricks… - Nature …, 2023 - nature.com
Post-infectious conditions present major health burdens but remain poorly understood. In
Chagas disease (CD), caused by Trypanosoma cruzi parasites, antiparasitic agents that …
Chagas disease (CD), caused by Trypanosoma cruzi parasites, antiparasitic agents that …
Side effects of benznidazole as treatment in chronic Chagas disease: fears and realities
R Viotti, C Vigliano, B Lococo, MG Alvarez… - Expert review of anti …, 2009 - Taylor & Francis
Chagas disease is caused by a parasite, Trypanosoma cruzi, transmitted primarily by a
triatomine insect and affects approximately 8 million people in Latin American countries. The …
triatomine insect and affects approximately 8 million people in Latin American countries. The …
[HTML][HTML] Comparative analysis of the kinomes of three pathogenic trypanosomatids: Leishmania major, Trypanosoma brucei and Trypanosoma cruzi
M Parsons, EA Worthey, PN Ward, JC Mottram - BMC genomics, 2005 - Springer
Abstract Background The trypanosomatids Leishmania major, Trypanosoma brucei and
Trypanosoma cruzi cause some of the most debilitating diseases of humankind: cutaneous …
Trypanosoma cruzi cause some of the most debilitating diseases of humankind: cutaneous …
Myocardial delayed enhancement by magnetic resonance imaging in patients with Chagas' disease: a marker of disease severity
CE Rochitte, PF Oliveira, JM Andrade, BM Ianni… - Journal of the American …, 2005 - jacc.org
Objectives: We sought to investigate whether myocardial delayed enhancement (MDE) by
magnetic resonance imaging (MRI) could quantify myocardial fibrosis (MF) in patients with …
magnetic resonance imaging (MRI) could quantify myocardial fibrosis (MF) in patients with …
Towards a paradigm shift in the treatment of chronic Chagas disease
R Viotti, B Alarcón de Noya… - Antimicrobial agents …, 2014 - Am Soc Microbiol
Treatment for Chagas disease with currently available medications is recommended
universally only for acute cases (all ages) and for children up to 14 years old. The World …
universally only for acute cases (all ages) and for children up to 14 years old. The World …
[HTML][HTML] Chagas heart disease: pathophysiologic mechanisms, prognostic factors and risk stratification
A Rassi Jr, A Rassi, JA Marin-Neto - Memorias do Instituto Oswaldo …, 2009 - SciELO Brasil
Chagas heart disease (CHD) results from infection with the protozoan parasite
Trypanosoma cruzi and is the leading cause of infectious myocarditis worldwide. It poses a …
Trypanosoma cruzi and is the leading cause of infectious myocarditis worldwide. It poses a …