A large body of evidence has demonstrated that exposure to childhood maltreatment at any
stage of development can have long-lasting consequences. It is associated with a marked …

Abstract Modern nosologies (eg, International Classification of Diseases, 11th edition [ICD-
11], Diagnostic and Statistical Manual of Mental Disorders, 5th edition [DSM–5]) for alcohol …

Background Substance use disorder (SUD) remains a significant public health issue. A
greater understanding of how genes and environment interact to regulate phenotypes …

Now revised and updated, this widely used text comprehensively reviews theories of
addiction to give students and professionals a multidisciplinary foundation for clinical …

The last 25 years have seen significant advances in our conceptualization of alcohol use
and alcohol use disorders within a developmental framework, along with advances in our …

While the risks of maternal alcohol abuse during pregnancy are well-established, several
preclinical studies suggest that chronic preconception alcohol consumption by either parent …

Alcoholism and drug dependence are common psychiatric disorders with a heritability of
about 50%; therefore genetic and environmental influences are equally important. Early-life …

Alcohol consumption during pregnancy and lactation is a widespread preventable cause of
neurodevelopmental impairment in newborns. While the harmful effects of gestational …

Although substance use and abuse may impact brain and behavior, it is still unclear why
some people become addicted while others do not. Neuroscientific theories explain …

Background: A growing body of evidence indicates that the density of tobacco retail outlets
around the home residence may influence tobacco use among youth and adults. The …