Psoriasis and metabolic syndrome: implications for the management and treatment of psoriasis

JJ Wu, A Kavanaugh, MG Lebwohl… - Journal of the …, 2022 - Wiley Online Library
Psoriasis is a chronic systemic inflammatory disorder associated with several comorbidities
in addition to the characteristic skin lesions. Metabolic syndrome (MetS) is the most frequent …

Psoriasis as an immune-mediated and inflammatory systemic disease: from pathophysiology to novel therapeutic approaches

A Campanati, A Marani, E Martina, F Diotallevi, G Radi… - Biomedicines, 2021 - mdpi.com
Psoriasis is an immune-mediated inflammatory disease, with a chronic relapsing-remitting
course, which affects 2–3% of the worldwide population. The progressive acquisitions of the …

The role of the interleukin‐23/Th17 pathway in cardiometabolic comorbidity associated with psoriasis

A Egeberg, P Gisondi, JM Carrascosa… - Journal of the …, 2020 - Wiley Online Library
Alterations in the innate and adaptive immunity underpin psoriasis pathophysiology, with the
Th17 cells subset now recognized as the fundamental cells in the key controlling pathway …

Shared pathways for neuroprogression and somatoprogression in neuropsychiatric disorders

G Morris, BK Puri, AJ Walker, M Maes… - Neuroscience & …, 2019 - Elsevier
Activated immune-inflammatory, oxidative and nitrosative stress (IO&NS) pathways and
consequent mitochondrial aberrations are involved in the pathophysiology of psychiatric …

Cytokines in psoriasis

CC de Alcantara, EMV Reiche, ANC Simão - Advances in clinical chemistry, 2021 - Elsevier
Psoriasis is chronic, immune-mediated, inflammatory disease with a multifactorial etiology
that affects the skin tissue and causes the appearance of dry and scaly lesions of anywhere …

Does weight loss reduce the severity and incidence of psoriasis or psoriatic arthritis? A critically appraised topic

SK Mahil, SM McSweeney, E Kloczko… - British Journal of …, 2019 - academic.oup.com
Clinical question Does weight loss reduce the severity and incidence of psoriasis or
psoriatic arthritis (PsA) in obese individuals? Background Obesity presents a rising public …

Endothelial dysfunction in psoriasis: an updated review

P Anyfanti, A Margouta, K Goulas, M Gavriilaki… - Frontiers in …, 2022 - frontiersin.org
Although psoriasis is predominantly a chronic inflammatory skin disorder, epidemiological
data provide a solid link between psoriasis, especially in its more severe forms, and …

Adipokines in the Skin and in Dermatological Diseases

D Kovács, F Fazekas, A Oláh, D Törőcsik - International Journal of …, 2020 - mdpi.com
Adipokines are the primary mediators of adipose tissue-induced and regulated systemic
inflammatory diseases; however, recent findings revealed that serum levels of various …

Aggressive weight-loss program with a ketogenic induction phase for the treatment of chronic plaque psoriasis: A proof-of-concept, single-arm, open-label clinical trial

G Castaldo, L Rastrelli, G Galdo, P Molettieri… - Nutrition, 2020 - Elsevier
Objectives A very low-calorie ketogenic diet (VLCKD) has been associated with a significant
reduction in visceral adipose tissue and ketone bodies that likely possess antiinflammatory …

Adiponectin, leptin and resistin in patients with psoriasis

S Słuczanowska-Głabowska, M Staniszewska… - Journal of Clinical …, 2023 - mdpi.com
Psoriasis is a common chronic, inflammatory skin disease characterised by keratinocyte
hyperproliferation, parakeratosis, and T-cell infiltration. Adipose tissue has an endocrine …