Fighting cancer with corroles

RD Teo, JY Hwang, J Termini, Z Gross… - Chemical …, 2017 - ACS Publications
Corroles are exceptionally promising platforms for the development of agents for
simultaneous cancer-targeting imaging and therapy. Depending on the element chelated by …

Synthesis of corroles and their heteroanalogs

R Orłowski, D Gryko, DT Gryko - Chemical Reviews, 2017 - ACS Publications
Corroles have come a long way from being a curiosity to being a mainstream research topic.
They are now regularly synthesized in numerous research laboratories worldwide with …

Recent Update on Targeting c-MYC G-Quadruplexes by Small Molecules for Anticancer Therapeutics

R Chaudhuri, S Bhattacharya, J Dash… - Journal of Medicinal …, 2020 - ACS Publications
Guanine-rich DNA sequences have the propensity to adopt four-stranded tetrahelical G-
quadruplex (G4) structures that are overrepresented in gene promoters. The structural …

A hitchhiker's guide to G-quadruplex ligands

D Monchaud, MP Teulade-Fichou - Organic & biomolecular chemistry, 2008 - pubs.rsc.org
Over the past decade, nucleic acid chemists have seen the spectacular emergence of
molecules designed to interact efficiently and selectively with a peculiar DNA structure …

Fabrication of a new corrole-based covalent organic framework as a highly efficient and selective chemosensor for heavy metal ions

Y Li, M Chen, Y Han, Y Feng, Z Zhang… - Chemistry of …, 2020 - ACS Publications
Since the widespread presence of metal ions in the ecosystem, especially heavy metal ions
that could bring severe damage to living organisms, the development of chemosensors for …

Platinum (II) complexes with dipyridophenazine ligands as human telomerase inhibitors and luminescent probes for G-quadruplex DNA

DL Ma, CM Che, SC Yan - Journal of the American Chemical …, 2009 - ACS Publications
A series of platinum (II) complexes containing dipyridophenazine (dppz) and C-
deprotonated 2-phenylpyridine (N∧ CH) ligands were prepared and assayed for G …

Stabilization of G-quadruplex DNA, inhibition of telomerase activity, and tumor cell apoptosis by organoplatinum (II) complexes with oxoisoaporphine

ZF Chen, QP Qin, JL Qin, YC Liu… - Journal of medicinal …, 2015 - ACS Publications
Two G-quadruplex ligands [Pt (La)(DMSO) Cl](Pt 1) and [Pt (Lb)(DMSO) Cl](Pt 2) have been
synthesized and fully characterized. The two complexes are more selective for SK-OV …

Survey of the year 2007 commercial optical biosensor literature

RL Rich, DG Myszka - Journal of Molecular Recognition: An …, 2008 - Wiley Online Library
In 2007, 1179 papers were published that involved the application of optical biosensors.
Reported developments in instrument hardware, assay design, and immobilization …

Hallmarks of anticancer and antimicrobial activities of corroles

VK Sharma, YG Assaraf, Z Gross - Drug Resistance Updates, 2023 - Elsevier
Corroles provide a remarkable opportunity for the development of cancer theranostic agents
among other porphyrinoids. While most transition metal corrole complexes are only …

Advances in the molecular design of potential anticancer agents via targeting of human telomeric DNA

B Maji, S Bhattacharya - Chemical Communications, 2014 - pubs.rsc.org
Telomerases are an attractive drug target to develop new generation drugs against cancer.
A telomere appears from the chromosomal termini and protects it from double-stranded DNA …