Basic MR relaxation mechanisms and contrast agent design

LM De León‐Rodríguez, AF Martins… - Journal of Magnetic …, 2015 - Wiley Online Library
The diagnostic capabilities of magnetic resonance imaging (MRI) have undergone
continuous and substantial evolution by virtue of hardware and software innovations and the …

The synthesis and application of polyamino polycarboxylic bifunctional chelating agents

L Lattuada, A Barge, G Cravotto… - Chemical Society …, 2011 - pubs.rsc.org
Bifunctional chelating agents (BFCAs) are molecules which contain two different moieties: a
strong metal chelating unit and a reactive functional group. The latter is directed to react with …

Water exchange in lanthanide complexes for MRI applications. Lessons learned over the last 25 years

P Caravan, D Esteban-Gómez… - Dalton …, 2019 - pubs.rsc.org
The water exchange rates of water molecules coordinated to the metal ion in lanthanide
complexes have been profusely investigated during the last 25 years, especially in the case …

Gd (DOTAla): a single amino acid Gd-complex as a modular tool for high relaxivity MR contrast agent development

E Boros, M Polasek, Z Zhang… - Journal of the American …, 2012 - ACS Publications
MR imaging at high magnetic fields benefits from an increased signal-to-noise ratio;
however T 1-based MR contrast agents show decreasing relaxivity (r 1) at higher fields. High …

Cyclen dithiocarbamate-functionalized silver nanoparticles as a probe for colorimetric sensing of thiram and paraquat pesticides via host–guest chemistry

JV Rohit, SK Kailasa - Journal of nanoparticle research, 2014 - Springer
We have developed a simple and rapid colorimetric method for on-site analysis of thiram
and paraquat using cyclen dithiocarbamate-functionalized silver nanoparticles (CN-DTC-Ag …

Reporter protein-targeted probes for magnetic resonance imaging

RC Strauch, DJ Mastarone, PA Sukerkar… - Journal of the …, 2011 - ACS Publications
Contrast agents for magnetic resonance imaging are frequently employed as experimental
and clinical probes. Drawbacks include low signal sensitivity, fast clearance, and …

Gd-AAZTA-MADEC, an improved blood pool agent for DCE-MRI studies on mice on 1 T scanners

DL Longo, F Arena, L Consolino, P Minazzi… - Biomaterials, 2016 - Elsevier
A novel MRI blood-pool contrast agent (Gd-AAZTA-MADEC) has been compared with
established blood pool agents for tumor contrast enhanced images and angiography …

Gold nanoparticles functionalised with stable, fast water exchanging Gd 3+ chelates as high relaxivity contrast agents for MRI

MF Ferreira, B Mousavi, PM Ferreira, CIO Martins… - Dalton …, 2012 - pubs.rsc.org
Gold nanoparticles functionalized with Gd3+ chelates displaying fast water exchange,
superb pH stability and inertness towards transmetalation with Zn2+ have been prepared …

New potential bimodal imaging contrast agents based on DOTA-like and porphyrin macrocycles

CP Gros, A Eggenspiller, A Nonat, JM Barbe… - MedChemComm, 2011 - pubs.rsc.org
A bifunctional chelator featuring (DO3A-AM)-Porphyrin units has been prepared. The high-
field relaxivity of the Gd complex is similar to those of currently available contrast agents …

A novel zinc bis (thiosemicarbazone) complex for live cell imaging

D Dayal, D Palanimuthu, SV Shinde… - JBIC Journal of …, 2011 - Springer
Fluorescent zinc complexes have recently attracted a lot of interest owing to their vast
applications in cellular imaging. We report the synthesis as well as physical, chemical and …