The apolipoprotein E locus (APOE) is associated with variations in the age of onset and risk
of Alzheimer's disease. The APOE4 allele increases the probability of disease at an earlier …

Inheritance of specific apolipoprotein E (apoE) alleles determines, in large part, the risk and
mean age of onset of late-onset familial and sporadic Alzheimer disease. The mechanism by …

Background: The APOE gene and its protein product is associated with a number of plasma
proteins like very-low density lipoprotein (VLDL), high density lipoprotein (HDL) …

Apolipoprotein E (APOE) is a lipid-transport protein abundantly expressed in most neurons
in the central nervous system. APOE-dependent alterations of the endocytic pathway can …

Three common protein isoforms of apolipoprotein E (apoE), encoded by the η2, η3, and η4
alleles of the APOE gene, differ in their association with cardiovascular and Alzheimer's …

Apolipoprotein E (apoE) is one of the major protein constituents of chylomicron and very‐low‐
density lipoprotein (VLDL) remnants and plays a central role as a ligand in the receptor …

Our purpose was to assess the effect of apolipoprotein (apo) E and apo A-IV isoform
variation on low density lipoprotein (LDL) cholesterol lowering response to the HMG CoA …

Abstract Background Cardiovascular diseases (CVDs) comprise major causes of death
worldwide, leading to extensive burden on populations and societies. Alterations in normal …

It has long been known that there is an extremely high degree of variability in both human
and nonhuman primates in terms of low density lipoprotein cholesterol (LDL-C) lowering in …

Human exposure to mercury is a serious problem of public health in Amazon. As in other
vulnerable populations throughout the world, Amazonian riverine populations are …