Implantation is an essential process during establishment of pregnancy in mammals. It is
initiated with the attachment of the blastocyst to a receptive uterine epithelium followed by its …

Rapid evolution driven by positive Darwinian selection is a recurrent theme in male
reproductive protein evolution. In contrast, positive selection has never been demonstrated …

A protein known as heat-shock factor-1 (HSF1) is a major transactivator of stress-inducible
genes in response to environmental changes, but it is also implicated in extra-embryonic …

Infertility affects 10% of reproductive-age women and is extremely heterogeneous in
etiology. The genetic contribution to female infertility is incompletely understood, and …

Infertility affects an estimated 10% of couples, and in roughly half of these cases the defect
can be traced to the man. Several groups have expressed the concern that male-infertility …

The CCCH tandem zinc finger protein, Zfp36l2, like its better-known relative tristetraprolin
(TTP), can decrease the stability of AU-rich element-containing transcripts in cell transfection …

BACKGROUND: Premature ovarian failure (POF) is a heterogeneous syndrome, possibly
due to mutations of genes involved in the normal development of the ovary and/or follicles …

There is an ongoing debate among reproductive endocrinologists and embryologists about
the indications for ICSI in the management of the infertile couple. Analysis of published …

Poor responders represent more than a third of women undergoing assisted reproduction.
Typically they are patients with advanced maternal age and low ovarian reserve. However …

BACKGROUND: A case of idiopathic primary infertility was attributed to a block in oocyte
meiosis affecting the transition between metaphase I and metaphase II. METHODS AND …