Scientific Opinion on a request for a review of a scientific publication concerning the zoonotic potential of ovine scrapie prions
EFSA Panel on Biological Hazards (BIOHAZ … - EFSA Journal, 2015 - Wiley Online Library
The factors that modulate the transmissibility of Transmissible Spongiform Encephalopathies
(TSE) and the approaches for the study of their zoonotic potential are reviewed. The paper …
(TSE) and the approaches for the study of their zoonotic potential are reviewed. The paper …
Characterization of goat prions demonstrates geographical variation of scrapie strains in Europe and reveals the composite nature of prion strains
Abstract Bovine Spongiform Encephalopathy (BSE) is the only animal prion which has been
recognized as a zoonotic agent so far. The identification of BSE in two goats raised the need …
recognized as a zoonotic agent so far. The identification of BSE in two goats raised the need …
Scrapie incidence and PRNP polymorphisms: rare small ruminant breeds of Sicily with TSE protecting genetic reservoirs
Background Transmissible spongiform encephalopathies (TSE) are fatal neurodegenerative
diseases of several mammalian species, including humans. In Italy, the active surveillance …
diseases of several mammalian species, including humans. In Italy, the active surveillance …
Further characterisation of transmissible spongiform encephalopathy phenotypes after inoculation of cattle with two temporally separated sources of sheep scrapie …
T Konold, R Nonno, J Spiropoulos, MJ Chaplin… - BMC Research …, 2015 - Springer
Background The infectious agent responsible for the bovine spongiform encephalopathy
(BSE) epidemic in Great Britain is a transmissible spongiform encephalopathy (TSE) strain …
(BSE) epidemic in Great Britain is a transmissible spongiform encephalopathy (TSE) strain …
Detection and partial discrimination of atypical and classical bovine spongiform encephalopathies in cattle and primates using real-time quaking-induced conversion …
E Levavasseur, AG Biacabe, E Comoy, A Culeux… - PLoS …, 2017 - journals.plos.org
The transmission of classical bovine spongiform encephalopathy (C-BSE) through
contaminated meat product consumption is responsible for variant Creutzfeldt-Jakob …
contaminated meat product consumption is responsible for variant Creutzfeldt-Jakob …
L-BSE experimentally transmitted to sheep presents as a unique disease phenotype
MM Simmons, MJ Chaplin, T Konold, C Casalone… - Veterinary …, 2016 - Springer
Apart from prion protein genotype, the factors determining the host range and susceptiblity
for specific transmissible spongiform encephalopathy agents remain unclear. It is known that …
for specific transmissible spongiform encephalopathy agents remain unclear. It is known that …
Protocol for further laboratory investigations into the distribution of infectivity of Atypical BSE
European Food Safety Authority - EFSA Journal, 2014 - Wiley Online Library
Abstract Information on the pathogenesis and tissue distribution of Atypical Bovine
Spongiform Encephalopathy (BSE) in cattle through the study of field cases and …
Spongiform Encephalopathy (BSE) in cattle through the study of field cases and …
Clinical, pathological, and molecular features of classical and L-type atypical-BSE in goats
E Vallino Costassa, A D'Angelo, M Mazza, D Meloni… - Plos one, 2018 - journals.plos.org
Monitoring of small ruminants for transmissible spongiform encephalopathies (TSEs) has
recently become more relevant after two natural scrapie suspected cases of goats were …
recently become more relevant after two natural scrapie suspected cases of goats were …
Acquired transmissibility of sheep-passaged L-type bovine spongiform encephalopathy prion to wild-type mice
H Okada, K Masujin, K Miyazawa, T Yokoyama - Veterinary Research, 2015 - Springer
L-type bovine spongiform encephalopathy (L-BSE) is an atypical form of BSE that is
transmissible to cattle and several lines of prion protein (PrP) transgenic mice, but not to wild …
transmissible to cattle and several lines of prion protein (PrP) transgenic mice, but not to wild …
Molecular characterisation of atypical BSE prions by mass spectrometry and changes following transmission to sheep and transgenic mouse models
A Gielbert, JK Thorne, JM Plater, L Thorne, PC Griffiths… - Plos one, 2018 - journals.plos.org
The prion hypothesis proposes a causal relationship between the misfolded prion protein
(PrPSc) molecular entity and the disease transmissible spongiform encephalopathy (TSE) …
(PrPSc) molecular entity and the disease transmissible spongiform encephalopathy (TSE) …