The altered activation or overexpression of protein kinases (PKs) is a major subject of
research in oncology and their inhibition using small molecules, protein kinases inhibitors …

We herein report the design and synthesis of new 1, 3, 5-triazine-based pyrazole derivatives
(5a–i) with anticancer activity targeting the epidermal growth factor (EGFR) tyrosine kinase …

2, 4-Thiazolidinedione (2, 4-TZD) is a versatile pharmacophore, a privileged scaffold, and a
remarkable sulphur-containing heterocyclic compound with diverse pharmacological …

Based on the previous studies that revealed the valuable role of pyrazole scaffold in cancer
management and VEGFR-2 inhibition, a new set of pyrazole conjugated with pyrazoline …

Squalene is a natural dehydrotriterpenic hydrocarbon (C30H50) with six double bonds, an
intermediate for the biosynthesis of phytosterol/cholesterol in plants/animals and humans …

The current study describes the synthesis, physicochemical characterization and cytotoxicity
evaluation of a new series of pyrrole derivatives in order to identify new bioactive molecules …

Pyrrolizidine alkaloids (PAs) are a widespread class of hepatotoxic heterocyclic organic
compounds found in approximately 3% of world flora. Some PAs have been shown to have …

A sulfonated amorphous carbon (AC-SO 3 H) was prepared from rice husk with sulfuric acid
and fully characterized using FT-IR spectroscopy, X-ray diffraction (XRD), scanning electron …

Hydrazone complexes of Cu (II), Co (II), Zn (II), Ni (II) and Pt (II) with N-isonicotinoyl-N′-(3-
metoxy-2 hydroxybenzaldehyde)-hydrazone (HL) were synthesized and characterized by …

Since VEGFR-2 plays a crucial role in tumor growth, angiogenesis, and metastasis, it is a
prospective target for cancer treatment. In this work, a series of 3-phenyl-4-(2-substituted …