Senescence in human mesenchymal stem cells: functional changes and implications in stem cell-based therapy

V Turinetto, E Vitale, C Giachino - International journal of molecular …, 2016 - mdpi.com
Regenerative medicine is extensively interested in developing cell therapies using
mesenchymal stem cells (MSCs), with applications to several aging-associated diseases …

Aging of mesenchymal stem cell: machinery, markers, and strategies of fighting

M Al-Azab, M Safi, E Idiiatullina, F Al-Shaebi… - Cellular & Molecular …, 2022 - Springer
Human mesenchymal stem cells (MSCs) are primary multipotent cells capable of
differentiating into osteocytes, chondrocytes, and adipocytes when stimulated under …

[HTML][HTML] Determination of protein carbonyls in plasma, cell extracts, tissue homogenates, isolated proteins: Focus on sample preparation and derivatization conditions

D Weber, MJ Davies, T Grune - Redox biology, 2015 - Elsevier
Protein oxidation is involved in regulatory physiological events as well as in damage to
tissues and is thought to play a key role in the pathophysiology of diseases and in the aging …

MSCs vs. iPSCs: Potential in therapeutic applications

K Thanaskody, AS Jusop, GJ Tye… - Frontiers in Cell and …, 2022 - frontiersin.org
Over the past 2 decades, mesenchymal stem cells (MSCs) have attracted a lot of interest as
a unique therapeutic approach for a variety of diseases. MSCs are capable of self-renewal …

Genetic stability of mesenchymal stromal cells for regenerative medicine applications: a fundamental biosafety aspect

S Neri - International journal of molecular sciences, 2019 - mdpi.com
Mesenchymal stem/stromal cells (MSC) show widespread application for a variety of clinical
conditions; therefore, their use necessitates continuous monitoring of their safety. The risk …

The influence of aging on the regenerative potential of human adipose derived mesenchymal stem cells

M Marędziak, K Marycz, KA Tomaszewski… - Stem cells …, 2016 - Wiley Online Library
Tissue regeneration using human adipose derived mesenchymal stem cells (hASCs) has
significant potential as a novel treatment for many degenerative bone and joint diseases …

Adipose-derived mesenchymal stem cells from the elderly exhibit decreased migration and differentiation abilities with senescent properties

M Liu, H Lei, P Dong, X Fu, Z Yang, Y Yang… - Cell …, 2017 - journals.sagepub.com
Adipose-derived stem cells (ASCs) can be applied extensively in the clinic because they can
be easily isolated and cause less donor-site morbidity; however, their application can be …

Extensive protein dosage compensation in aneuploid human cancers

KM Schukken, JM Sheltzer - Genome research, 2022 - genome.cshlp.org
Aneuploidy is a hallmark of human cancers, but the effects of aneuploidy on protein
expression remain poorly understood. To uncover how chromosome copy number changes …

Dental follicle cells: roles in development and beyond

T Zhou, J Pan, P Wu, R Huang, W Du… - Stem cells …, 2019 - Wiley Online Library
Dental follicle cells (DFCs) are a group of mesenchymal progenitor cells surrounding the
tooth germ, responsible for cementum, periodontal ligament, and alveolar bone formation in …

Curcumin-loaded mesoporous silica nanoparticles/nanofiber composites for supporting long-term proliferation and stemness preservation of adipose-derived stem …

S Mashayekhi, S Rasoulpoor, S Shabani… - International journal of …, 2020 - Elsevier
The present research aims to design and develop a sustained drug release system to
support the long-term proliferation of human adipose-derived stem cells (hADSCs) without …