Multicomponent reactions (MCRs) receive increasing attention because they address both
diversity and complexity in organic synthesis. Thus, in principle diverse sets of relatively …

Chiral molecules containing asymmetric carbon centers bonded with nitrogen are ubiquitous
in nature and also form important structural fragments in both natural and man-made …

The catalysis by primary and secondary amines of electrophilic substitution reactions in the
R-position of carbonyl compounds and related reactions via enamine intermediates is called …

After an initial period of validating asymmetric organocatalysis by using a wide range of
important model reactions that constitute the essential tools of organic synthesis, the time …

Proteinogenic and non-proteinogenic R-amino acids (R-AAs) constitute one of the five most
important families of natural products1 and are essential molecules in many scientific areas …

Asymmetric organocatalysis is becoming one of the main tools for the synthesis of chiral
compounds that are needed as medicines, crop protection agents, and other bioactive …

Direct and rapid heating by microwave irradiation in combination with sealed vessel
processing in many cases enables reactions to be carried out in a fraction of the time …

The asymmetric Mannich reaction ranks among the most potent enantioselective and
diastereoselective C–C-bond forming reactions. In recent years, organocatalysed versions …

The enantioselective production of compounds is a central theme in current research. The
broad utility of synthetic chiral molecules as single-enantiomer pharmaceuticals, in …

Microwave technology has become very important in synthesis and it is reasonable to assert
that there are now very few areas of synthetic organic chemistry that have not been shown to …