High levels of penetrating cryoprotectants (CPAs) can eliminate ice formation during
cryopreservation of cells, tissues, and organs to cryogenic temperatures. But CPAs become …

Transplantation of hematopoietic stem cells (HSCs) has been successfully developed as a
part of treatment protocols for a large number of clinical indications, and cryopreservation of …

Dimethyl sulfoxide (DMSO) is an important aprotic solvent that can solubilize a wide variety
of otherwise poorly soluble polar and nonpolar molecules. This, coupled with its apparent …

Ab initio protein folding is one of the major unsolved problems in computational biology
owing to the difficulties in force field design and conformational search. We developed a …

Abstract Aflatoxin B1 (AFB1) is a mycotoxin often found in food and livestock feed. It can
affect human and animal health and is especially damaging to the liver. This study aims to …

Background: ORGANIC SOLVENTS are widely used in cell biology experiments. Despite
increasing the solubility, they have some moderate toxic effects. Therefore, selecting the …

Multi-drug chemotherapy has been one of the most popular strategies for the treatment of
malignant tumors, and has achieved desirable therapeutic outcomes. The objective of the …

Cisplatin, carboplatin, nedaplatin, and oxaliplatin are widely used in contemporary
oncology; however, their ototoxic and neurotoxic side effects are quite different as discussed …

Analysis of the interplay between cell proliferation and death has been greatly advantaged
by the development of CNS slice preparations. In slices, interactions between neurons and …

Exposure to benzene, toluene and xylene in the human population may pose a health risk.
We tested a working hypothesis that these test chemicals cause cellular toxicity to a non …