Abstract Background Streptococcus pneumoniae (Pneumococcus) has remained a leading
cause of fatal infections such as pneumonia, meningitis, and sepsis. Moreover, this …

Background The pathogenicity of pneumococcus with high morbidity, mortality, and multi-
drug resistance patterns has been increasing. The limited coverage of the licensed …

Meningitis infection is one of the major threats during Hajj season in Mecca. Meningitis
vaccines are available, but their uses are limited in some countries due to religious reasons …

Serotype-specific protection against Streptococcus pneumoniae is an important limitation of
the current polysaccharide-based vaccines. To prevent serotype replacement, reduce …

Background Rotaviral diarrhoea kills about half a million children annually in developing
countries and accounts for one third of diarrhea related hospitalizations. Drugs and vaccines …

Although cocaine abuse and addiction continue to cause serious health and societal
problems, an FDA-approved medication to treat cocaine addiction has yet to be developed …

Streptococcus pneumoniae (pneumococcus) is a human pathogen that can cause otitis
media, pneumonia and, in severe cases, meningitis and bacteremia. The pneumococcus …

The Zika virus infections have reached epidemic proportions in the Latin American countries
causing severe birth defects and neurological disorders. While several organizations have …

Abstract Background Ebola viruses (EBOVs) cause severe hemorrhagic fever with a high
mortality rate. At present, there are no licensed vaccines or efficient therapies to combat …

Background Plasmodium falciparum apical membrane antigen-1 (AMA1) is a leading
malaria vaccine candidate antigen that is expressed by sporozoite, liver and blood stage …