Measurements of continuous variables are made in all branches of medicine, aiding in the
diagnosis and treatment of patients. In clinical practice it is helpful to label individuals as …

Background Osteoprotegerin (OPG), sclerostin and DKK1 constitute opposite bone turnover
inhibitors, OPG inhibiting osteoclastogenesis while sclerostin and DKK1 exerting their …

Background In 2013, New York began requiring hospitals to follow protocols for the early
identification and treatment of sepsis. However, there is controversy about whether more …

Importance The Third International Consensus Definitions Task Force defined sepsis as “life-
threatening organ dysfunction due to a dysregulated host response to infection.” The …

Importance The death of a pediatric patient with sepsis motivated New York to mandate
statewide sepsis treatment in 2013. The mandate included a 1-hour bundle of blood …

Prognosis and prognostic research: Developing a prognostic model | The BMJ Skip to main
content Intended for healthcare professionals Access provided by Google Indexer Subscribe …

Multivariable regression models are of fundamental importance in all areas of science in
which empirical data must be analyzed. This book proposes a systematic approach to …

In developing regression models, data analysts are often faced with many predictor
variables that may influence an outcome variable. After more than half a century of research …

Background. A number of US observational studies reported an increased mortality risk with
higher intact parathyroid hormone (iPTH), calcium and/or phosphate. The existence of such …

ABSTRACT Background: Serum 25-hydroxyvitamin D [25 (OH) D] concentration has been
linked to mortality in several studies, but appropriate cutoffs to define risk categories are …