Epitope identification and discovery using phage display libraries: applications in vaccine development and diagnostics

LF Wang, M Yu - Current drug targets, 2004 - ingentaconnect.com
Antigenic epitopes are the part (contact points) of an antigen involved in specific interaction
with the antigen-binding site (the paratope) of an antibody or a T-cell receptor. Detailed …

[图书][B] Phage display in biotechnology and drug discovery

SS Sidhu, CR Geyer - 2015 - books.google.com
The book provides a comprehensive view of the impact and promise of phage display in
drug discovery and biotechnology. Building on the success of its previous edition, the book …

Development of a peptide ELISA for discrimination between serological responses to equine herpesvirus type 1 and 4

A Lang, M de Vries, S Feineis, E Müller… - Journal of virological …, 2013 - Elsevier
A peptide-based enzyme-linked immunosorbent assay (ELISA) for discrimination between
serological responses to equine herpesvirus type 1 (EHV-1) and 4 (EHV-4) was developed …

Identification of equine herpesvirus-1 antigens recognized by cytotoxic T lymphocytes

G Soboll, JM Whalley, MT Koen… - Journal of general …, 2003 - microbiologyresearch.org
Equine herpesvirus-1 (EHV-1) causes serious disease in horses throughout the world,
despite the frequent use of vaccines. CTLs are thought to be critical for protection from …

Identification of epitopes in the nucleocapsid protein of Nipah virus using a linear phage‐displayed random peptide library

M Eshaghi, WS Tan, K Yusoff - Journal of medical virology, 2005 - Wiley Online Library
A random peptide library of heptamers displayed on the surface of M13 bacteriophage was
used to identify specific epitopes of antibodies in pooled sera of swine naturally infected by …

Selection of phage-display library peptides recognizing ethanol targets on proteins

H Anni, O Nikolaeva, Y Israel - Alcohol, 2001 - Elsevier
There is a forthcoming link between chronic alcohol consumption and proteins covalently
modified by ethanol metabolites and their antibodies. To identify sensitive probes of protein …

Identification of a major immunogenic region of equine herpesvirus-1 glycoprotein E and its application to enzyme-linked immunosorbent assay

K Andoh, M Takasugi, HYAH Mahmoud, S Hattori… - Veterinary …, 2013 - Elsevier
A major immunogenic region of equine herpesvirus (EHV)-1 glycoprotein E (gE) was
identified. Firstly, the various fragments of EHV-1 gE were expressed as fusion proteins with …

[HTML][HTML] Purification of polyclonal anti-conformational antibodies for use in affinity selection from random peptide phage display libraries: a study using the hydatid …

AJ Read, CG Gauci, MW Lightowlers - Journal of chromatography B, 2009 - Elsevier
The use of polyclonal antibodies to screen random peptide phage display libraries often
results in the recognition of a large number of peptides that mimic linear epitopes on various …

[图书][B] Antiviral chemotherapeutic agents against equine herpesvirus type 1: the mechanism of antiviral effects of porphyrin derivatives

GV Rybachuk - 2009 - search.proquest.com
Abstract Equine Herpesvirus-1 (EHV-1) is an important ubiquitous enzootic equine
pathogen, causing significant economic losses to the horse industry. Despite extensive …

Identification of peptides specific for antibodies in vitiligo using a phage library

Z Jadali, MB Eslami, MH Sanati… - Clinical and …, 2005 - academic.oup.com
Patients with vitiligo produce specific autoantibodies that can be detected in their sera.
These antibodies are believed to play a role in the pathogenesis of this disease. A random …