Age-related changes in the knee meniscus
A Tsujii, N Nakamura, S Horibe - The Knee, 2017 - Elsevier
Background Aging is the most prominent risk factor for the development of osteoarthritis
(OA), which affects knees and causes major health burdens. Meniscal dysfunction mostly …
(OA), which affects knees and causes major health burdens. Meniscal dysfunction mostly …
Mitogen-activated protein kinases as therapeutic targets in osteoarthritis
RF Loeser, EA Erickson, DL Long - Current opinion in …, 2008 - journals.lww.com
MAP kinase inhibition has the potential to slow disease progression in osteoarthritis and
also might reduce pain; however, safety concerns have limited the use of general MAP …
also might reduce pain; however, safety concerns have limited the use of general MAP …
MMP-13 enzyme and pH responsive theranostic nanoplatform for osteoarthritis
Q Lan, R Lu, H Chen, Y Pang, F Xiong, C Shen… - Journal of …, 2020 - Springer
Stimulus-responsive therapy permits precise control of therapeutic effect only at lesion of
interest, which determines it a promising method for diagnosis and imaging-guided …
interest, which determines it a promising method for diagnosis and imaging-guided …
[HTML][HTML] Pro-inflammatory stimulation of meniscus cells increases production of matrix metalloproteinases and additional catabolic factors involved in osteoarthritis …
AV Stone, RF Loeser, KS Vanderman, DL Long… - Osteoarthritis and …, 2014 - Elsevier
Objective Meniscus injury increases the risk of osteoarthritis; however, the biologic
mechanism remains unknown. We hypothesized that pro-inflammatory stimulation of …
mechanism remains unknown. We hypothesized that pro-inflammatory stimulation of …
Glucocorticoid treatment in acute respiratory distress syndrome: An overview on mechanistic insights and clinical benefit
J Zhang, P Ge, J Liu, Y Luo, H Guo, G Zhang… - International Journal of …, 2023 - mdpi.com
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS), triggered by various
pathogenic factors inside and outside the lungs, leads to diffuse lung injury and can result in …
pathogenic factors inside and outside the lungs, leads to diffuse lung injury and can result in …
[HTML][HTML] Emodin protects against concanavalin A-induced hepatitis in mice through inhibiting activation of the p38 MAPK-NF-κB signaling pathway
J Xue, F Chen, J Wang, S Wu, M Zheng… - Cellular Physiology and …, 2015 - karger.com
Background/Aims: To investigate the effects of emodin on concanavalin A (Con A)-induced
hepatitis in mice and to elucidate its underlying molecular mechanisms. Methods: A …
hepatitis in mice and to elucidate its underlying molecular mechanisms. Methods: A …
Phytochemicals with protective effects against acute pancreatitis: a review of recent literature
Y Tang, M Sun, Z Liu - Pharmaceutical Biology, 2022 - Taylor & Francis
Context Acute pancreatitis (AP) is an acute abdominal inflammatory disease with episodes
ranging from mild to fulminant symptoms which could include necrosis, systemic …
ranging from mild to fulminant symptoms which could include necrosis, systemic …
Chlorogenic acid ameliorated concanavalin A-induced hepatitis by suppression of Toll-like receptor 4 signaling in mice
Y Yuan, X Gong, L Zhang, R Jiang, J Yang… - International …, 2017 - Elsevier
Chlorogenic acid (CGA), one of the most abundant dietary polyphenolic compounds, has
been reported to exhibit anti-inflammatory ability. However, the hepatoprotective effects and …
been reported to exhibit anti-inflammatory ability. However, the hepatoprotective effects and …
Carvedilol attenuates l-arginine induced acute pancreatitis in rats through modulation of oxidative stress and inflammatory mediators
EM El Morsy, MAE Ahmed - Chemico-biological interactions, 2020 - Elsevier
Acute pancreatitis (AP) is a sudden pancreatic inflammation accompanied by an excessive
reactive oxygen species production that provokes inflammation. The present study …
reactive oxygen species production that provokes inflammation. The present study …
Severity of pancreatitis‑associated intestinal mucosal barrier injury is reduced following treatment with the NADPH oxidase inhibitor apocynin
W Deng, A Abliz, S Xu, R Sun… - Molecular …, 2016 - spandidos-publications.com
Recent studies demonstrated that apocynin, a nicotinamide adenine dinucleotide phosphate
(NADPH) oxidase (NOX) inhibitor, significantly decreased acute pancreatitis‑associated …
(NADPH) oxidase (NOX) inhibitor, significantly decreased acute pancreatitis‑associated …