Background Aging is the most prominent risk factor for the development of osteoarthritis
(OA), which affects knees and causes major health burdens. Meniscal dysfunction mostly …

MAP kinase inhibition has the potential to slow disease progression in osteoarthritis and
also might reduce pain; however, safety concerns have limited the use of general MAP …

Stimulus-responsive therapy permits precise control of therapeutic effect only at lesion of
interest, which determines it a promising method for diagnosis and imaging-guided …

Objective Meniscus injury increases the risk of osteoarthritis; however, the biologic
mechanism remains unknown. We hypothesized that pro-inflammatory stimulation of …

Acute lung injury/acute respiratory distress syndrome (ALI/ARDS), triggered by various
pathogenic factors inside and outside the lungs, leads to diffuse lung injury and can result in …

Background/Aims: To investigate the effects of emodin on concanavalin A (Con A)-induced
hepatitis in mice and to elucidate its underlying molecular mechanisms. Methods: A …

Context Acute pancreatitis (AP) is an acute abdominal inflammatory disease with episodes
ranging from mild to fulminant symptoms which could include necrosis, systemic …

Chlorogenic acid (CGA), one of the most abundant dietary polyphenolic compounds, has
been reported to exhibit anti-inflammatory ability. However, the hepatoprotective effects and …

Acute pancreatitis (AP) is a sudden pancreatic inflammation accompanied by an excessive
reactive oxygen species production that provokes inflammation. The present study …

Recent studies demonstrated that apocynin, a nicotinamide adenine dinucleotide phosphate
(NADPH) oxidase (NOX) inhibitor, significantly decreased acute pancreatitis‑associated …