Cholangiocarcinoma 2020: the next horizon in mechanisms and management

JM Banales, JJG Marin, A Lamarca… - Nature reviews …, 2020 - nature.com
Cholangiocarcinoma (CCA) includes a cluster of highly heterogeneous biliary malignant
tumours that can arise at any point of the biliary tree. Their incidence is increasing globally …

Molecular targeted therapies: ready for “prime time” in biliary tract cancer

A Lamarca, J Barriuso, MG McNamara, JW Valle - Journal of hepatology, 2020 - Elsevier
The prognosis for patients with biliary tract cancers (cholangiocarcinoma and gallbladder
cancer) is poor, while the incidence of these cancers is increasing. Most patients are …

New horizons for precision medicine in biliary tract cancers

JW Valle, A Lamarca, L Goyal, J Barriuso, AX Zhu - Cancer discovery, 2017 - AACR
Biliary tract cancers (BTC), including cholangiocarcinoma and gallbladder cancer, are poor-
prognosis and low-incidence cancers, although the incidence of intrahepatic …

Nomograms in oncology: more than meets the eye

VP Balachandran, M Gonen, JJ Smith… - The lancet …, 2015 - thelancet.com
Nomograms are widely used as prognostic devices in oncology and medicine. With the
ability to generate an individual probability of a clinical event by integrating diverse …

Gallbladder cancer in the 21st century

R Kanthan, JL Senger, S Ahmed… - Journal of …, 2015 - Wiley Online Library
Gallbladder cancer (GBC) is an uncommon disease in the majority of the world despite
being the most common and aggressive malignancy of the biliary tree. Early diagnosis is …

[HTML][HTML] Gallbladder cancer: expert consensus statement

TA Aloia, N Járufe, M Javle, SK Maithel, JC Roa… - Hpb, 2015 - Elsevier
Abstract An American Hepato-Pancreato-Biliary Association (AHPBA)-sponsored consensus
meeting of expert panellists was convened on 15 January 2014 to review current evidence …

SWOG S0809: a phase II intergroup trial of adjuvant capecitabine and gemcitabine followed by radiotherapy and concurrent capecitabine in extrahepatic …

E Ben-Josef, KA Guthrie, AB El-Khoueiry… - Journal of Clinical …, 2015 - ascopubs.org
Purpose The role of postoperative therapy in extrahepatic cholangiocarcinoma (EHCC) or
gallbladder carcinoma (GBCA) is unknown. S0809 was designed to estimate 2-year survival …

Gallbladder cancer: diagnosis, surgical management, and adjuvant therapies

L Hickman, C Contreras - Surgical Clinics, 2019 - surgical.theclinics.com
Gallbladder cancer (GBC) is a relatively rare occurrence with a poor prognosis (overall 5-
year survival is 50% for stage I cancers and 3% for stage IV cancers 1). Surgical resection is …

Adjuvant chemotherapy with gemcitabine and cisplatin compared to observation after curative intent resection of cholangiocarcinoma and muscle invasive gallbladder …

A Stein, D Arnold, J Bridgewater, D Goldstein… - BMC cancer, 2015 - Springer
Background Despite complete resection, disease-free survival (DFS) of patients with
cholangiocarcinoma (CCA) is less than 65% after one year and not more than 35% after …

Current standards and future perspectives in adjuvant treatment for biliary tract cancers

A Lamarca, J Edeline, MG McNamara, RA Hubner… - Cancer treatment …, 2020 - Elsevier
Biliary tract cancer, including cholangiocarcinoma (CCA) and gallbladder cancer (GBC) are
rare tumours with a rising incidence. Prognosis is poor, since most patients are diagnosed …