Heart failure with preserved ejection fraction in humans and mice: embracing clinical complexity in mouse models

C Withaar, CSP Lam, GG Schiattarella… - European heart …, 2021 - academic.oup.com
Heart failure (HF) with preserved ejection fraction (HFpEF) is a multifactorial disease
accounting for a large and increasing proportion of all clinical HF presentations. As a clinical …

Immunometabolic mechanisms of heart failure with preserved ejection fraction

GG Schiattarella, P Alcaide, G Condorelli… - Nature cardiovascular …, 2022 - nature.com
Heart failure with preserved ejection fraction (HFpEF) is increasing in prevalence worldwide,
already accounting for at least half of all cases of heart failure. As most patients with HFpEF …

Burden of comorbidities and functional and cognitive impairments in elderly patients at the initial diagnosis of heart failure and their impact on total mortality: the …

K Murad, DC Goff, TM Morgan, GL Burke, TM Bartz… - JACC: Heart Failure, 2015 - jacc.org
Objectives: The purpose of this study was to determine the prevalence of clinically relevant
comorbidities and measures of physical and cognitive impairment in elderly persons with …

Clinical phenotypes in heart failure with preserved ejection fraction

R Samson, A Jaiswal, PV Ennezat… - Journal of the …, 2016 - Am Heart Assoc
Over the past 2 decades, the syndrome of heart failure with preserved ejection fraction
(HFpEF) received a lot of attention. 1–19 However, little therapeutic progress was made. 20 …

Vascular and microvascular endothelial function in heart failure with preserved ejection fraction

S Maréchaux, R Samson, E Van Belle, J Breyne… - Journal of cardiac …, 2016 - Elsevier
Background Assessment of vascular endothelial function lacks consistency, and
microvascular endothelial function has been only partly assessed in heart failure with …

[HTML][HTML] The economic case for US hospitals to revise their approach to heart failure readmission reduction

A Zohrabian, JM Kapp, EJ Simoes - Annals of translational …, 2018 - ncbi.nlm.nih.gov
To support hospital decision makers in their effort to reduce readmissions, the authors of this
perspective present employer self-insurance as a potential incentive strategy, in particular …

Prognostic significance of serum cholinesterase level in patients with acute decompensated heart failure with preserved ejection fraction: insights from the PURSUIT …

M Seo, T Yamada, S Tamaki, S Hikoso… - Journal of the …, 2020 - Am Heart Assoc
Background Malnutrition is one of the most important comorbidities in patients with heart
failure with preserved ejection fraction. We recently reported the prognostic significance of …

Blood pressure levels and adverse cardiovascular outcomes in heart failure: A systematic review and meta‐analysis

S Seidu, CA Lawson, SK Kunutsor… - European Journal of …, 2024 - Wiley Online Library
Aim Existing data on the association between blood pressure levels and adverse
cardiovascular outcomes in patients with heart failure (HF) are inconsistent. The optimal …

Atrial functional versus ventricular functional mitral regurgitation: prognostic implications

SA Hirji, CL Cote, H Javadikasgari, A Malarczyk… - The Journal of Thoracic …, 2022 - Elsevier
Background Atrial functional mitral regurgitation (FMR) occurs because of left atrial dilatation
or atrial fibrillation in heart failure with preserved left ventricular (LV) function, contrary to …

Secondary mitral regurgitation in heart failure with reduced or preserved left ventricular ejection fraction

PV Ennezat, S Maréchaux, P Pibarot, TH Le Jemtel - Cardiology, 2013 - karger.com
Secondary mitral regurgitation (MR) has been extensively studied in heart failure due to
reduced ejection fraction. In contrast, the occurrence and the pathogenesis of secondary MR …