Biomarkers in spinal cord injury: from prognosis to treatment

LF Rodrigues, V Moura-Neto, TCLS e Spohr - Molecular neurobiology, 2018 - Springer
Spinal cord injury (SCI) is considered an incurable condition, having a heterogenous
recovery and uncertain prognosis. Therefore, a reliable prediction of the improvement in the …

Fighting for recovery on multiple fronts: The past, present, and future of clinical trials for spinal cord injury

VA Dietz, N Roberts, K Knox, S Moore… - Frontiers in cellular …, 2022 - frontiersin.org
Through many decades of preclinical research, great progress has been achieved in
understanding the complex nature of spinal cord injury (SCI). Preclinical research efforts …

Cell therapies for spinal cord injury: trends and challenges of current clinical trials

RD Bartlett, S Burley, M Ip, JB Phillips, D Choi - Neurosurgery, 2020 - journals.lww.com
Cell therapies have the potential to revolutionize the treatment of spinal cord injury. Basic
research has progressed significantly in recent years, with a plethora of cell types now …

Improving diagnostic workup following traumatic spinal cord injury: advances in biomarkers

S Schading, TM Emmenegger, P Freund - Current neurology and …, 2021 - Springer
Abstract Purpose of Review Traumatic spinal cord injury (SCI) is a life-changing event with
drastic implications for patients due to sensorimotor impairment and autonomous …

Early clinical predictors of functional recovery following traumatic spinal cord injury: a population-based study of 143 patients

TO Wichmann, MH Jensen, H Kasch… - Acta Neurochirurgica, 2021 - Springer
Background Traumatic spinal cord injuries (TSCI) are associated with uncertainty regarding
the prognosis of functional recovery. The aim of the present study was to evaluate the …

Extent of traumatic spinal cord injury is lesion level dependent and predictive of recovery: a multicenter neuroimaging study

S Schading-Sassenhausen, D Pfyffer… - Journal of …, 2024 - liebertpub.com
Assessing the extent of the intramedullary lesion after spinal cord injury (SCI) might help to
improve prognostication. However, because the neurological level of injury impacts the …

A beginner's guide to data stewardship and data sharing

MP Dijkers - Spinal Cord, 2019 - nature.com
Study design A narrative review of principles, benefits and disadvantages, as well as
methods of research data sharing. Objectives To assist prospective Spinal Cord authors and …

Steroid inhibited Serpina3n expression which was positively correlated with the degrees of spinal cord injury

H Chen, L Wu, Y Zhang, W Ding, Y Xiaofan - Heliyon, 2024 - cell.com
Aims The aim of our project was to identify proteins associated with the extent of spinal cord
injury (SCI) and subsequent long-term neurological recovery. Methods Through proteomic …

Significance of physical factors on activities of daily living in patients with tetraplegia after spinal cord injury: a retrospective study

K Yun, J Lim, O Kim - BMC Sports Science, Medicine and Rehabilitation, 2024 - Springer
Background Tetraplegia is a debilitating sequela of spinal cord injury (SCI). However,
comprehensive approaches for determining the influence of various factors on activities of …

Placebo response in neuropathic pain after spinal cord injury: a meta-analysis of individual participant data

CR Jutzeler, FM Warner, JJ Cragg, J Haefeli… - Journal of Pain …, 2018 - Taylor & Francis
Background Understanding factors associated with high placebo responses in clinical trials
increases the likelihood of detecting a meaningful treatment effect. The aim of the present …