Background Patient participation in clinical trials is vital for knowledge advancement and
outcomes improvement. Few adult cancer patients participate in trials. Although patient …

Financial barriers to clinical trial enrollment are an area of active investigation. Financial
toxicity as a concept describes how high costs and financial burden can lead to …

The severe acute respiratory syndrome coronavirus 2 pandemic has drastically altered all
facets of clinical care and research. Clinical research in hepatology has had a rich tradition …

Background Participation in randomized controlled trials (RCTs) may be quite demanding
and could represent an important burden for patients. We aimed to explore this research …

Importance Logistical challenges such as travel time and distance to a clinical trial site can
be a barrier to patient participation. The association of remote technology use and other …

Cancer clinical trials are critical for testing new treatments, yet less than 5% of patients with
cancer enroll in these trials. Minority groups, elderly individuals, and rural populations are …

Parkinson disease (PD) is highly prevalent among neurodegenerative diseases, affecting a
diverse patient population. Despite a general willingness of patients to participate in clinical …

Background Clinical trials are an important therapeutic option for patients with cancer.
Although financial burden in cancer treatment is well documented, the financial burden …

Intercity patient mobility reflects the geographic mismatch between healthcare resources
and the population, and has rarely been studied with big data at large spatial scales. In this …

Importance Several ophthalmic diseases disproportionately affect racial and ethnic minority
patients, yet most clinical trials struggle to enroll cohorts that are demographically …