Clathrin-mediated endocytosis is a key process in vesicular trafficking that transports a wide
range of cargo molecules from the cell surface to the interior. Clathrin-mediated endocytosis …

Abstract The Rho GTPases—RHOA, RAC1 and CDC42—are small GTP binding proteins
that regulate basic biological processes such as cell locomotion, cell division and …

ASH1 mRNA localizes to the bud tip in Saccharomyces cerevisiae to establish asymmetry of
HO expression, important for mating type switching. To visualize real time localization of the …

All cell types polarize, at least transiently, during division or to generate specialized shapes
and functions. This capacity extends from yeast to mammals, and it is now clear that many …

Endocytosis includes a number of processes by which cells internalize segments of their
plasma membrane, enclosing a wide variety of material from outside the cell. Endocytosis …

Asymmetric cell division, which includes cell polarization and cytokinesis, is essential for
generating cell diversity during development. The budding yeast Saccharomyces cerevisiae …

Endocytosis depends on an extensive network of interacting proteins that execute a series of
distinct subprocesses. Previously, we used live-cell imaging of six budding-yeast proteins to …

Actin polymerization often occurs at the plasma membrane to drive the protrusion of
lamellipodia and filopodia at the leading edge of migrating cells. A role for actin …

In budding yeast, many proteins involved in endocytic internalization, including adaptors
and actin cytoskeletal proteins, are localized to cortical patches of differing protein …

Microtubules and actin filaments play important roles in mitosis, cell signaling, and motility.
Thus these cytoskeletal filaments are the targets of a growing number of anti-cancer drugs …