Microglia are so versatile that they not only provide immune surveillance for central nervous
system, but participate in neural circuitry development, brain blood vessels formation, blood …

Neuroinflammation, a core pathological feature observed in several neurodegenerative
diseases, including Alzheimer's disease (AD), is rapidly gaining attention as a target in …

Differential RNA expression is becoming increasingly valuable in evaluating tumor
heterogeneity for a better understanding of malignant tumors and guiding personalized …

Alzheimer's disease (AD) is a debilitating neurodegenerative disease characterised by the
accumulation of amyloid-beta and tau in the brain, leading to the progressive loss of memory …

Alzheimer's disease (AD) is the most common neurodegenerative disease, with sporadic
form being the predominant type. Neuroinflammation plays a critical role in accelerating …

Alzheimer's disease is the primary neurodegenerative disease affecting the elderly
population. Despite the first description of its pathology over a century ago, its precise cause …

Sialic acids, commonly found as the terminal carbohydrate on the glycocalyx of mammalian
cells, are pivotal checkpoint inhibitors of the innate immune system, particularly within the …

Tauopathies as one of the typical neurodegenerative diseases are characterized by
pathologically aggregated tau in neuron and glia, which causes dysfunction, synapse loss …

Alzheimer's disease (AD) is a neurodegenerative condition that poses multiple challenges
for disease diagnosis and treatment. Biomarker-based assays are one of the important tools …

Human microglia are critically involved in Alzheimer's disease (AD) progression, as shown
by genetic and molecular studies. However, their role in tau pathology progression in human …