Recent updates on mechanisms of resistance to 5-fluorouracil and reversal strategies in colon cancer treatment
S Azwar, HF Seow, M Abdullah, M Faisal Jabar… - Biology, 2021 - mdpi.com
Simple Summary Acquired resistance to chemotherapy by cancer cells is the predominant
factor in chemotherapy failure, which ultimately leads to disease progression and death …
factor in chemotherapy failure, which ultimately leads to disease progression and death …
Wnt/β‑catenin signaling: Causes and treatment targets of drug resistance in colorectal cancer
GX Zhu, D Gao, ZZ Shao, L Chen… - Molecular …, 2021 - spandidos-publications.com
Colorectal cancer (CRC) is the third most common malignant tumor in humans.
Chemotherapy is used for the treatment of CRC. However, the effect of chemotherapy …
Chemotherapy is used for the treatment of CRC. However, the effect of chemotherapy …
Expression and prognostic significance of CBX2 in colorectal cancer: database mining for CBX family members in malignancies and vitro analyses
H Zhou, Y Xiong, Z Liu, S Hou, T Zhou - Cancer cell international, 2021 - Springer
Abstract Background The Chromobox (CBX) domain protein family, a core component of
polycomb repressive complexes 1, is involved in transcriptional repression, cell …
polycomb repressive complexes 1, is involved in transcriptional repression, cell …
Early-onset colorectal cancer
V Nfonsam, E Wusterbarth, A Gong, P Vij - Surgical Oncology Clinics of …, 2022 - Elsevier
Colorectal cancer (CRC) is the third most common cancer in the world and is a leading
cause of morbidity and mortality. 1 In the United States, it is associated with the third highest …
cause of morbidity and mortality. 1 In the United States, it is associated with the third highest …
Dampened inflammation and improved survival after CXCL5 administration in murine lupus via myeloid and neutrophil pathways
Objective To determine the efficacy of CXCL5 administration in lupus‐prone MRL/lpr (Fas
lpr) mice and elucidate its working mechanisms. Methods CXCL5 expression in blood …
lpr) mice and elucidate its working mechanisms. Methods CXCL5 expression in blood …
Whole exome sequencing identifies MAP3K1, MSH2, and MLH1 as potential cancer‐predisposing genes in familial early‐onset colorectal cancer
The incidence of early‐onset colorectal cancer (CRC), which affects people under 50, is
increasing for unknown reasons. Additionally, no underlying genetic cause is found in 20 …
increasing for unknown reasons. Additionally, no underlying genetic cause is found in 20 …
Epigenetics and therapeutic targets in gastrointestinal malignancies
GP Nagaraju, P Kasa, B Dariya, N Surepalli… - Drug Discovery …, 2021 - Elsevier
Gastrointestinal (GI) malignancies account for substantial mortality and morbidity worldwide.
They are generally promoted by dysregulated signal transduction and epigenetic pathways …
They are generally promoted by dysregulated signal transduction and epigenetic pathways …
Decolourisation of direct red dye 81 from aqueous solutions by SnO2/H2O2 hybrid process
SZ Ghazanfari, J Jaafari, SD Ashrafi… - International Journal of …, 2023 - Taylor & Francis
The aim of this study was to use tin oxide (SnO2) nanoparticle along with hydrogen peroxide
(H2O2) and to evaluate their potential in removing direct red 81 (DR 81) dye from aqueous …
(H2O2) and to evaluate their potential in removing direct red 81 (DR 81) dye from aqueous …
Krüppel‐like factor 6 promotes odontoblastic differentiation through regulating the expression of dentine sialophosphoprotein and dentine matrix protein 1 genes
Z Chen, H Xie, J Yuan, Y Lan… - International Endodontic …, 2021 - Wiley Online Library
Aim To investigate the potential role of Krüppel‐like factor 6 (KLF6) in the odontoblastic
differentiation of immortalized dental papilla mesenchymal cells (iMDP‐3) cells …
differentiation of immortalized dental papilla mesenchymal cells (iMDP‐3) cells …
Hydroxytyrosol's effect on the expression of apoptosis and oxidative stress related genes in BE (2)-C neuroblastoma cell line
S Pakravan, M Hemmati-Dinarvand, M Moghaddasi… - Gene Reports, 2023 - Elsevier
Neuroblastoma (NB) is defined as a type of tumor that involves the autonomic nervous
system. Oxidative stress (OxS) resulted from dopamine (DA) oxidation and the reduction of …
system. Oxidative stress (OxS) resulted from dopamine (DA) oxidation and the reduction of …