In the field of biomedical optics, optical scattering has traditionally limited the range of
imaging within tissue to a depth of one millimetre. A recently developed class of wavefront …

Nanomedicine is defined as “the application of nanotechnology to medicine, including the
use of nanometer-sized carrier materials for facilitating disease diagnosis, disease treatment …

Optical microscopy has been a fundamental tool of biological discovery for more than three
centuries, but its in vivo tissue imaging ability has been restricted by light scattering to …

The success of fluorescence experiments requires attention to experimental details and an
understanding of the instrumentation. There are also many potential artifacts that can distort …

Metal nanoshells are a class of nanoparticles with tunable optical resonances. In this article,
an application of this technology to thermal ablative therapy for cancer is described. By …

Photon penetration into living tissue is highly dependent on the absorption and scattering
properties of tissue components. The near-infrared region of the spectrum offers certain …

New technologies for imaging molecules, particularly optical technologies, are increasingly
being used to understand the complexity, diversity and in vivo behaviour of cancers.'Omic' …

Optical imaging is a powerful modality in biological discovery. The mainstream of optical
interrogations, however, largely relies on microscopy, which imposes depth limitations on …

Morphological observations have driven the course of biology ever since the first
microscope was built in the late sixteenth century. Molecular imaging is a rapidly emerging …

Optical sensing of specific molecular targets and pathways deep inside living mice has
become possible as a result of a number of advances. These include design of …