Wingless ligands, a family of secreted proteins, are critically involved in organ development
and tissue homeostasis by ensuring balanced rates of stem cell proliferation, cell death and …

Wnt signaling determines major developmental processes in the embryonic state and
regulates maintenance, self-renewal and differentiation of adult mammalian tissue stem …

Mammalian reproductive performance declines rapidly with advanced maternal age. This
effect is largely attributed to the exponential increase in chromosome segregation errors in …

Wnt family members are best known for their roles in cell fate determination, differentiation,
proliferation and apoptosis during embryonic development. Wnt signaling becomes effective …

Decidua is a transient uterine tissue shared by mammals with hemochorial placenta and is
essential for pregnancy. The decidua is infiltrated by many immune cells promoting …

During decidualization in rodents, uterine stroma undergoes extensive reprograming into
distinct cells, forming the discrete regions defined as the primary decidual zone (PDZ), the …

Endometrial cells perceive and respond to their microenvironment forming the basis of
endometrial homeostasis. Errors in endometrial cell signaling are responsible for a wide …

In view of emerging drug-resistant tuberculosis (TB), host-directed adjunct therapies are
urgently needed to improve treatment outcomes with currently available anti-TB therapies …

The developmental origins and evolutionary histories of cell types, tissues, and organs
contribute to the ways in which their dysfunction produces disease. In mammals, the nature …

Among nearly 100 mammalian species, implantation can be suspended at blastocyst stage
for a certain time and reactivated under favorable conditions, a phenomenon known as …