[HTML][HTML] Crosstalk between Mu-Opioid receptors and neuroinflammation: Consequences for drug addiction and pain
J Cuitavi, JV Torres-Pérez, JD Lorente… - Neuroscience & …, 2023 - Elsevier
Abstract Mu-Opioid Receptors (MORs) are well-known for participating in analgesia,
sedation, drug addiction, and other physiological functions. Although MORs have been …
sedation, drug addiction, and other physiological functions. Although MORs have been …
Data-driven study on resting-state functional magnetic resonance imaging during early abstinence of alcohol dependence in male patients and its predictive value for …
R Deng, X Yang, Y Meng, Y Tao, H Wang, X Li, W Wei… - BMC psychiatry, 2022 - Springer
Background Alcohol dependence is a mental disorder with a high relapse rate. However,
specific neuroimaging biomarkers have not been determined for alcohol dependence and …
specific neuroimaging biomarkers have not been determined for alcohol dependence and …
Functional connectivity of nucleus accumbens and medial prefrontal cortex with other brain regions during early-abstinence is associated with alcohol dependence …
X Yang, Y Meng, Y Tao, R Deng, H Wang, X Li… - Frontiers in …, 2021 - frontiersin.org
Background: Alcohol dependence (AD) is a chronic recurrent brain disease that causes a
heavy disease burden worldwide, partly due to high relapse rates after detoxification …
heavy disease burden worldwide, partly due to high relapse rates after detoxification …
Kappa opioid receptor blockade in the nucleus accumbens shell prevents sex-dependent alcohol deprivation effect induced by inflammatory pain
JD Lorente, J Cuitavi, Y Campos-Jurado… - Pain, 2022 - journals.lww.com
Pain-induced negative affect reduces life quality of patients by increasing psychiatric
comorbidities, including alcohol use disorders (AUDs). Indeed, clinical data suggest pain as …
comorbidities, including alcohol use disorders (AUDs). Indeed, clinical data suggest pain as …
[HTML][HTML] Sex-dependent effect of inflammatory pain on negative affective states is prevented by kappa opioid receptors blockade in the nucleus accumbens shell
JD Lorente, J Cuitavi, L Rullo, S Candeletti… - …, 2024 - Elsevier
Pain comorbidities include several psychological disorders, such as anxiety and anhedonia.
However, the way pain affects male and female individuals and by which mechanism is not …
However, the way pain affects male and female individuals and by which mechanism is not …
Sensory-motor response elicited by first time intraoral administered ethanol after trigeminal neuropathic injury
RD Andrade-Gonzalez, E Perrusquia-Hernández… - Alcohol, 2022 - Elsevier
Recent findings have shown a relationship between alcohol use disorders (AUD) and
chronic pain. Preclinical models have demonstrated that chronic pain, including trigeminal …
chronic pain. Preclinical models have demonstrated that chronic pain, including trigeminal …
[PDF][PDF] Tackling the opioid crisis: Novel mechanisms and clinical perspectives
H Leduc‐Pessah, T Trang - Journal of Neuroscience Research, 2022 - researchgate.net
The isolation of morphine by Friedrich Serturner in 1804 unlocked the powerful essence of
opium. There are now a plethora of natural, synthetic, and semi-synthetic opioid analgesics …
opium. There are now a plethora of natural, synthetic, and semi-synthetic opioid analgesics …