A functional perspective on phenotypic heterogeneity in microorganisms
M Ackermann - Nature Reviews Microbiology, 2015 - nature.com
Most microbial communities consist of a genetically diverse assembly of different organisms,
and the level of genetic diversity plays an important part in community properties and …
and the level of genetic diversity plays an important part in community properties and …
Stochastic developmental variation, an epigenetic source of phenotypic diversity with far-reaching biological consequences
G Vogt - Journal of Biosciences, 2015 - Springer
This article reviews the production of different phenotypes from the same genotype in the
same environment by stochastic cellular events, nonlinear mechanisms during patterning …
same environment by stochastic cellular events, nonlinear mechanisms during patterning …
Reduced phenotypic plasticity evolves in less predictable environments
Phenotypic plasticity is a prominent mechanism for coping with variable environments, and a
key determinant of extinction risk. Evolutionary theory predicts that phenotypic plasticity …
key determinant of extinction risk. Evolutionary theory predicts that phenotypic plasticity …
Gene loss and compensatory evolution promotes the emergence of morphological novelties in budding yeast
Deleterious mutations are generally considered to be irrelevant for morphological evolution.
However, they could be compensated by conditionally beneficial mutations, thereby …
However, they could be compensated by conditionally beneficial mutations, thereby …
Plant-derived antifungal agent poacic acid targets β-1, 3-glucan
A rise in resistance to current antifungals necessitates strategies to identify alternative
sources of effective fungicides. We report the discovery of poacic acid, a potent antifungal …
sources of effective fungicides. We report the discovery of poacic acid, a potent antifungal …
Using phenotypic plasticity to understand the structure and evolution of the genotype–phenotype map
Deciphering the genotype–phenotype map necessitates relating variation at the genetic
level to variation at the phenotypic level. This endeavour is inherently limited by the …
level to variation at the phenotypic level. This endeavour is inherently limited by the …
[HTML][HTML] Phenotypic heterogeneity in fungi: importance and methodology
Phenotypic heterogeneity describes the variation that exists between individual cells, spores
or other biological entities within genetically-uniform populations of fungi or other organisms …
or other biological entities within genetically-uniform populations of fungi or other organisms …
Role of genetic architecture in phenotypic plasticity
Phenotypic plasticity, the ability of an organism to display different phenotypes across
environments, is widespread in nature. Plasticity aids survival in novel environments …
environments, is widespread in nature. Plasticity aids survival in novel environments …
Genome editing to generate sake yeast strains with eight mutations that confer excellent brewing characteristics
Sake yeast is mostly diploid, so the introduction of recessive mutations to improve brewing
characteristics requires considerable effort. To construct sake yeast with multiple excellent …
characteristics requires considerable effort. To construct sake yeast with multiple excellent …
Cucurbitacin B exerts antiaging effects in yeast by regulating autophagy and oxidative stress
Y Lin, Y Kotakeyama, J Li, Y Pan… - Oxidative Medicine …, 2019 - Wiley Online Library
The budding yeast Saccharomyces cerevisiae has been used as a model organism for the
basic mechanism of aging, which provides useful assay systems for measuring both …
basic mechanism of aging, which provides useful assay systems for measuring both …