Microfluidic organs-on-chips
An organ-on-a-chip is a microfluidic cell culture device created with microchip manufacturing
methods that contains continuously perfused chambers inhabited by living cells arranged to …
methods that contains continuously perfused chambers inhabited by living cells arranged to …
[HTML][HTML] Microfluidic platforms for cell cultures and investigations
This review covers several aspects of microfluidic devices used for culturing and monitoring
of both adherent and non-adherent cells, including a multitude of applications. A comparison …
of both adherent and non-adherent cells, including a multitude of applications. A comparison …
Fungal brain infection modelled in a human-neurovascular-unit-on-a-chip with a functional blood–brain barrier
The neurovascular unit, which consists of vascular cells surrounded by astrocytic end-feet
and neurons, controls cerebral blood flow and the permeability of the blood–brain barrier …
and neurons, controls cerebral blood flow and the permeability of the blood–brain barrier …
A microfluidic 3D in vitro model for specificity of breast cancer metastasis to bone
Cancer metastases arise following extravasation of circulating tumor cells with certain
tumors exhibiting high organ specificity. Here, we developed a 3D microfluidic model to …
tumors exhibiting high organ specificity. Here, we developed a 3D microfluidic model to …
Natural bone-mimicking nanopore-incorporated hydroxyapatite scaffolds for enhanced bone tissue regeneration
Background A considerable number of studies has been carried out to develop alloplastic
bone graft materials such as hydroxyapatite (HAP) that mimic the hierarchical structure of …
bone graft materials such as hydroxyapatite (HAP) that mimic the hierarchical structure of …
A therapeutic convection–enhanced macroencapsulation device for enhancing β cell viability and insulin secretion
K Yang, ED O'Cearbhaill, SS Liu… - Proceedings of the …, 2021 - National Acad Sciences
Islet transplantation for type 1 diabetes treatment has been limited by the need for lifelong
immunosuppression regimens. This challenge has prompted the development of …
immunosuppression regimens. This challenge has prompted the development of …
Microfluidics for neuronal cell and circuit engineering
The widespread adoption of microfluidic devices among the neuroscience and neurobiology
communities has enabled addressing a broad range of questions at the molecular, cellular …
communities has enabled addressing a broad range of questions at the molecular, cellular …
Multiscale, hierarchically patterned topography for directing human neural stem cells into functional neurons
Various biophysical and biochemical factors are important for determining the fate of neural
stem cells (NSCs). Among biophysical signals, topographical stimulation by …
stem cells (NSCs). Among biophysical signals, topographical stimulation by …
Microfluidic systems for stem cell-based neural tissue engineering
Neural tissue engineering aims at developing novel approaches for the treatment of
diseases of the nervous system, by providing a permissive environment for the growth and …
diseases of the nervous system, by providing a permissive environment for the growth and …
Stem cell culture and differentiation in microfluidic devices toward organ-on-a-chip
Microfluidic lab-on-a-chip provides a new platform with unique advantages to mimic
complex physiological microenvironments in vivo and has been increasingly exploited to …
complex physiological microenvironments in vivo and has been increasingly exploited to …