For decades, demands associated with the predictable life-history cycle have been
considered stressful and have not been distinguished from stress that occurs in association …

In addition to the classic genomic mechanism of steroid action mediated by activation of
intracellular nuclear receptors, there is now extensive evidence that steroids also activate …

O objetivo deste estudo consiste em reunir dados bibliográficos que descrevam o perfil
terapêutico do canabidiol (CBD), o principal componente não psicoativo da planta …

One hypothesis to account for the onset and severity of neurological disorders is the loss of
trophic support. Indeed, changes in the levels and activities of brain-derived neurotrophic …

Glucocorticoids act rapidly at the paraventricular nucleus (PVN) to inhibit stress-excitatory
neurons and limit excessive glucocorticoid secretion. The signaling mechanism underlying …

Há relatos da utilização da planta Cannabis sativa para fins medicinais no tratamento de
diversas doenças. Sua utilização é milenar e atualmente a planta vem sendo estudada para …

Recent empirical research, mostly done on humans, recognizes that individuals'
physiological state affects levels of cooperation. An individual's internal state may affect the …

Hemophagocytic lymphohistiocytosis (HLH) is extremely rare in the neonatal period. The
incidence of neonatal HLH is not confirmed and may range from 1 in 50,000 to 150,000. The …

Glucocorticoids are stress hormones that play central roles in the immediate and slower
adaptive responses of the brain and body to new behavioral experience. The exact …

The hypothalamus is a part of the brain that is critical for sustaining life through its
homeostatic control and integrative regulation of the autonomic nervous system and …