Cancer-associated cachexia—understanding the tumour macroenvironment and microenvironment to improve management
JM Argilés, FJ López-Soriano, B Stemmler… - Nature Reviews …, 2023 - nature.com
Cachexia is a devastating, multifactorial and often irreversible systemic syndrome
characterized by substantial weight loss (mainly of skeletal muscle and adipose tissue) that …
characterized by substantial weight loss (mainly of skeletal muscle and adipose tissue) that …
Update on the treatment of cancer cachexia
K Nishie, T Nishie, S Sato, M Hanaoka - Drug Discovery Today, 2023 - Elsevier
Cancer cachexia is a complex multifaceted syndrome involving functional impairment and
changes in body composition that cannot be reversed by nutritional support. Cancer …
changes in body composition that cannot be reversed by nutritional support. Cancer …
Synthetic approaches to the new drugs approved during 2021
EL McInturff, SP France, CA Leverett… - Journal of Medicinal …, 2023 - ACS Publications
Each year, new drugs are introduced to the market, representing structures that have affinity
for biological targets implicated in human diseases and conditions. These new chemical …
for biological targets implicated in human diseases and conditions. These new chemical …
Involvement of the gut microbiota in cancer cachexia
BN VanderVeen, TD Cardaci… - … of Physiology-Cell …, 2024 - journals.physiology.org
Cancer cachexia, or the unintentional loss of body weight in patients with cancer, is a
multiorgan and multifactorial syndrome with a complex and largely unknown etiology; …
multiorgan and multifactorial syndrome with a complex and largely unknown etiology; …
The effects of synbiotics supplementation on reducing chemotherapy-induced side effects in women with breast cancer: a randomized placebo-controlled double-blind …
Y Khazaei, A Basi, ML Fernandez, H Foudazi… - … Medicine and Therapies, 2023 - Springer
Background The prevalence of breast cancer and its mortality rate are increasing rapidly
among women worldwide. On other hand, the courses of chemotherapy as the main …
among women worldwide. On other hand, the courses of chemotherapy as the main …
The contribution of tumor derived exosomes to cancer cachexia
Cancer cachexia is defined as unintentional weight loss secondary to neoplasia and is
associated with poor prognosis and outcomes. Cancer cachexia associated weight loss …
associated with poor prognosis and outcomes. Cancer cachexia associated weight loss …
Exploring heterogeneity: A dive into preclinical models of cancer cachexia
F Morena, AR Cabrera… - American Journal of …, 2024 - journals.physiology.org
Cancer cachexia (CC) is a multifactorial and complex syndrome experienced by up to 80%
of patients with cancer and implicated in∼ 40% of cancer-related deaths. Given its …
of patients with cancer and implicated in∼ 40% of cancer-related deaths. Given its …
Mirtazapine versus megestrol in the treatment of anorexia–cachexia syndrome in patients with advanced cancer: a randomized, double-blind, controlled phase II …
OLS Almeida, E Ferriolli, RCC Taveira, MG Rosenburg… - Cancers, 2023 - mdpi.com
Simple Summary This study compared mirtazapine with megestrol in the management of
cancer-related anorexia–cachexia syndrome in patients with advanced cancer. This is a …
cancer-related anorexia–cachexia syndrome in patients with advanced cancer. This is a …
Mechanisms of Ovarian Cancer-Associated Cachexia
CS Callaway, LM Mouchantat, BG Bitler… - Endocrinology, 2024 - academic.oup.com
Cancer-associated cachexia occurs in 50% to 80% of cancer patients and is responsible for
20% to 30% of cancer-related deaths. Cachexia limits survival and treatment outcomes, and …
20% to 30% of cancer-related deaths. Cachexia limits survival and treatment outcomes, and …
[HTML][HTML] An Assessment of Behavioral Risk Factors in Oncology Patients
An evaluation of the behavioral risk factors that contribute to the incidence and evolution of
cancer in oncology patients was conducted through a cross-sectional study using a …
cancer in oncology patients was conducted through a cross-sectional study using a …