The blood–brain barrier (BBB) is a dynamic interface responsible for maintaining the central
nervous system homeostasis. Its unique characteristics allow protecting the brain from …

Hemorrhagic transformation (HT) is a common complication of ischemic stroke that is
exacerbated by thrombolytic therapy. Methods to better prevent, predict, and treat HT are …

Blood–brain barrier (BBB) disruption occurs early enough to be within the thrombolytic time
window, and this early ischemic BBB damage is closely associated with hemorrhagic …

Background and purpose In patients with acute ischemic stroke treated with reperfusion
therapy we aimed to evaluate whether pretreatment blood–brain barrier (BBB) leakage is …

The significance of the hypoxia component of stroke injury is highlighted by hypermetabolic
brain tissue enriched with arachidonic acid (AA), a 22: 6n-3 polyunsaturated fatty acid. In an …

The blue azo dye, Evans blue, has a MW of 1.0 kDa. A notable property of Evans blue is its
propensity to bind serum albumin. The dye can, therefore, be used to measure the …

Computer models in medical diagnosis are being developed to help physicians differentiate
between healthy patients and patients with disease. These models can aid in successful …

Fast and accurate diagnosis of stroke is crucial for the immediate application of the right
therapy to patients. However, rapid diagnosis is still a challenge since an ischemic stroke …

Objective: Depression after stroke or poststroke depression (PSD) has a negative impact on
the rehabilitation process and the associated rehabilitation outcome. Consequently, defining …

Introduction: Hemorrhagic transformation (HT) is a complication of reperfusion therapy for
acute ischemic stroke. Blood–brain barrier (BBB) disruption is a crucial step toward HT; …