The crown and the scepter: roles of the protein corona in nanomedicine
Engineering nanomaterials are increasingly considered promising and powerful biomedical
tools or devices for imaging, drug delivery, and cancer therapies, but few nanomaterials …
tools or devices for imaging, drug delivery, and cancer therapies, but few nanomaterials …
Recent advances in understanding the protein corona of nanoparticles and in the formulation of “stealthy” nanomaterials
R Rampado, S Crotti, P Caliceti, S Pucciarelli… - … in bioengineering and …, 2020 - frontiersin.org
In the last decades, the staggering progress in nanotechnology brought around a wide and
heterogeneous range of nanoparticle-based platforms for the diagnosis and treatment of …
heterogeneous range of nanoparticle-based platforms for the diagnosis and treatment of …
Nanoparticle protein corona: from structure and function to therapeutic targeting
Nanoparticle (NP)-based therapeutics have ushered in a new era in translational medicine.
However, despite the clinical success of NP technology, it is not well-understood how NPs …
However, despite the clinical success of NP technology, it is not well-understood how NPs …
Cloaking nanoparticles with protein corona shield for targeted drug delivery
Targeted drug delivery using nanoparticles can minimize the side effects of conventional
pharmaceutical agents and enhance their efficacy. However, translating nanoparticle-based …
pharmaceutical agents and enhance their efficacy. However, translating nanoparticle-based …
Interplay of protein corona and immune cells controls blood residency of liposomes
F Giulimondi, L Digiacomo, D Pozzi, S Palchetti… - Nature …, 2019 - nature.com
In vivo liposomes, like other types of nanoparticles, acquire a totally new 'biological
identity'due to the formation of a biomolecular coating known as the protein corona that …
identity'due to the formation of a biomolecular coating known as the protein corona that …
Vacancies on 2D transition metal dichalcogenides elicit ferroptotic cell death
S Xu, H Zheng, R Ma, D Wu, Y Pan, C Yin… - Nature …, 2020 - nature.com
Sustainable developments of nanotechnology necessitate the exploration of structure-
activity relationships (SARs) at nano-bio interfaces. While ferroptosis may contribute in the …
activity relationships (SARs) at nano-bio interfaces. While ferroptosis may contribute in the …
Emerging understanding of the protein corona at the nano-bio interfaces
Upon entering the physiological environment, nanoparticles (NPs) are immediately
surrounded by a complex and tightly bound layer of biomolecules, or '(hard) protein corona' …
surrounded by a complex and tightly bound layer of biomolecules, or '(hard) protein corona' …
Protein nanoparticle charge and hydrophobicity govern protein corona and macrophage uptake
SM Pustulka, K Ling, SL Pish… - ACS Applied Materials & …, 2020 - ACS Publications
Protein nanoparticles are biomaterials composed entirely of proteins, with the protein
sequence and structure determining the nanoparticle physicochemical properties. Upon …
sequence and structure determining the nanoparticle physicochemical properties. Upon …
Biocompatibility of nanomaterials and their immunological properties
TR Kyriakides, A Raj, TH Tseng, H Xiao… - Biomedical …, 2021 - iopscience.iop.org
Nanomaterials (NMs) have revolutionized multiple aspects of medicine by enabling novel
sensing, diagnostic, and therapeutic approaches. Advancements in processing and …
sensing, diagnostic, and therapeutic approaches. Advancements in processing and …
Protein bio-corona: critical issue in immune nanotoxicology
With the expansion of the nanomedicine field, the knowledge focusing on the behavior of
nanoparticles in the biological milieu has rapidly escalated. Upon introduction to a complex …
nanoparticles in the biological milieu has rapidly escalated. Upon introduction to a complex …