Prodrugs are developed to increase the therapeutic properties of drugs and reduce their
side effects. Polyprodrugs emerged as highly efficient prodrugs produced by the …

Illicit drug-related incidents such as traffic accidents and sexual assaults are gaining
epidemic proportions worldwide. Besides, there is the rampant use of drugs at some critical …

Two-or one-electron-mediated difunctionalizations of internal alkenes represent
straightforward approaches to assemble molecular complexity by the simultaneous …

Heroin is an opioid agonist commonly abused for its rewarding effects. Since its synthesis at
the end of the nineteenth century, its popularity as a recreational drug has ebbed and …

Abstract Coronavirus Disease 2019 (COVID-19) has been a global health crisis since it was
first identified in December 2019. In addition to fever, cough, headache, and shortness of …

There are conflicting results about sex differences in the response to opioids for pain control
and the role of potential influencing factors of these differences has not been investigated …

In this study, we report a novel and facile colorimetric assay based on silver citrate-coated
Au@ Ag nanoparticles (Au@ AgNPs) as a chemosensor for the naked-eye detection of …

Pain is an unpleasant sensory and emotional experience that affects every aspect of a
patient's life and which may be treated through different pharmacological and non …

Despite increased attention to cancer pain, pain prevalence in patients with cancer has not
improved over the last decade and one third of cancer patients on anticancer therapy and …

Background The species composition of a microbial community is rarely fixed and often
experiences fluctuations of varying degrees and at varying frequencies. These perturbations …