Cerebral Plasmodium falciparum malaria: The role of PfEMP1 in its pathogenesis and immunity, and PfEMP1‐based vaccines to prevent it
Malaria, a mosquito‐borne infectious disease caused by parasites of the genus Plasmodium
continues to be a major health problem worldwide. The unicellular Plasmodium‐parasites …
continues to be a major health problem worldwide. The unicellular Plasmodium‐parasites …
[HTML][HTML] Investigating the pathogenesis of severe malaria: a multidisciplinary and cross-geographical approach
SC Wassmer, TE Taylor, PK Rathod… - The American journal …, 2015 - ncbi.nlm.nih.gov
More than a century after the discovery of Plasmodium spp. parasites, the pathogenesis of
severe malaria is still not well understood. The majority of malaria cases are caused by …
severe malaria is still not well understood. The majority of malaria cases are caused by …
Increased circulation time of Plasmodium falciparum underlies persistent asymptomatic infection in the dry season
CM Andrade, H Fleckenstein, R Thomson-Luque… - Nature Medicine, 2020 - nature.com
The dry season is a major challenge for Plasmodium falciparum parasites in many malaria
endemic regions, where water availability limits mosquito vectors to only part of the year …
endemic regions, where water availability limits mosquito vectors to only part of the year …
A prospective analysis of the Ab response to Plasmodium falciparum before and after a malaria season by protein microarray
PD Crompton, MA Kayala, B Traore… - Proceedings of the …, 2010 - National Acad Sciences
Abs are central to malaria immunity, which is only acquired after years of exposure to
Plasmodium falciparum (Pf). Despite the enormous worldwide burden of malaria, the targets …
Plasmodium falciparum (Pf). Despite the enormous worldwide burden of malaria, the targets …
Plasmodium falciparum Erythrocyte Membrane Protein 1 Diversity in Seven Genomes – Divide and Conquer
TS Rask, DA Hansen, TG Theander… - PLoS computational …, 2010 - journals.plos.org
The var gene encoded hyper-variable Plasmodium falciparum erythrocyte membrane
protein 1 (PfEMP1) family mediates cytoadhesion of infected erythrocytes to human …
protein 1 (PfEMP1) family mediates cytoadhesion of infected erythrocytes to human …
Evidence for the involvement of VAR2CSA in pregnancy-associated malaria
In Plasmodium falciparum–endemic areas, pregnancy-associated malaria (PAM) is an
important health problem. The condition is precipitated by accumulation of parasite-infected …
important health problem. The condition is precipitated by accumulation of parasite-infected …
Immune effector mechanisms in malaria
K Marsh, S Kinyanjui - Parasite immunology, 2006 - Wiley Online Library
That humans in endemic areas become immune to malaria offers encouragement to the
idea of developing protective vaccines. However natural immunity is relatively inefficient …
idea of developing protective vaccines. However natural immunity is relatively inefficient …
Genome-wide analysis of heterochromatin associates clonally variant gene regulation with perinuclear repressive centers in malaria parasites
JJ Lopez-Rubio, L Mancio-Silva, A Scherf - Cell host & microbe, 2009 - cell.com
Clonally variant gene families underlie phenotypic plasticity in Plasmodium falciparum, a
process indispensable for survival of the pathogen in its human host. Differential …
process indispensable for survival of the pathogen in its human host. Differential …
Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children
T Lavstsen, L Turner, F Saguti… - Proceedings of the …, 2012 - National Acad Sciences
The clinical outcome of Plasmodium falciparum infections ranges from asymptomatic
parasitemia to severe malaria syndromes associated with high mortality. The virulence of P …
parasitemia to severe malaria syndromes associated with high mortality. The virulence of P …
Identification and genome-wide prediction of DNA binding specificities for the ApiAP2 family of regulators from the malaria parasite
TL Campbell, EK De Silva, KL Olszewski… - PLoS …, 2010 - journals.plos.org
The molecular mechanisms underlying transcriptional regulation in apicomplexan parasites
remain poorly understood. Recently, the Apicomplexan AP2 (ApiAP2) family of DNA binding …
remain poorly understood. Recently, the Apicomplexan AP2 (ApiAP2) family of DNA binding …