In electrically nonexcitable cells, Ca2+ influx is essential for regulating a host of kinetically
distinct processes involving exocytosis, enzyme control, gene regulation, cell growth and …

Endothelium is a community of endothelial cells (ECs), which line the blood and lymphatic
vessels, thus forming an interface between the tissues and the blood or lympha. This …

Mitochondrial Ca2+ efflux is linked to numerous cellular activities and pathophysiological
processes. Although it is established that an Na+-dependent mechanism mediates …

It has long been known that endothelial Ca2+ signals drive angiogenesis by recruiting
multiple Ca2+-sensitive decoders in response to pro-angiogenic cues, such as vascular …

Calcium oscillations suppress mitochondrial movements along the microtubules to support
on-demand distribution of mitochondria. To activate this mechanism, Ca2+ targets a yet …

Mitochondria extrude protons across their inner membrane to generate the mitochondrial
membrane potential (ΔΨ m) and pH gradient (ΔpH m) that both power ATP synthesis …

Mitochondria couple cellular metabolic state with Ca2+ transport processes. They therefore
control not only their own intra-organelle [Ca2+], but they also influence the entire cellular …

Disturbances in vascular function contribute to the development of several diseases of
increasing prevalence and thereby contribute significantly to human mortality and morbidity …

Mitochondria form junctions with the sarco/endoplasmic reticulum (SR/ER), which support
signal transduction and biosynthetic pathways and affect organellar distribution. Recently …

Dopamine‐releasing neurons within the Substantia nigra (SN DA) are particularly
vulnerable to degeneration compared to other dopaminergic neurons. The age‐dependent …