Objective Parental environmental exposures can strongly influence descendant risks for
adult disease. How paternal obesity changes the sperm chromatin leading to the acquisition …

Abstract Protein arginine methyltransferase 1 (PRMT1), the predominant type I protein
arginine methyltransferase, plays a crucial role in normal biological functions by catalyzing …

Background Anorexia nervosa (AN) is a complex debilitating disease characterized by
intense fear of weight gain and excessive exercise. It is the deadliest of any psychiatric …

Obesity has become a major global problem that significantly confers an increased risk of
developing life‐threatening complications, including type 2 diabetes mellitus, fatty liver …

Abnormal epigenetic modifications are involved in the regulation of Warburg effect in tumor
cells. Protein arginine methyltransferases (PRMTs) mediate arginine methylation and have …

Objective Fetal exposures may impact offspring epigenetic signatures and adiposity. The
authors hypothesized that maternal metabolic traits associate with cord blood DNA …

Adipose tissues are central in controlling metabolic homeostasis and failure in their
preservation is associated with age-related metabolic disorders. The exact role of mature …

Protein arginine methyltransferase 1 (PRMT1) methylates a variety of histone and
nonhistone protein substrates to regulate multiple cellular functions such as transcription …

Background Exposure to cold temperature stimulates the sympathetic nervous system that
activates β-adrenergic receptor signals in brown and beige adipocytes, leading to the …

Background and aims Hepatic lipogenesis is elevated in nutrient abundant conditions to
convert the excess carbohydrate into triacylglycerol (TAG). Fatty acyl moiety of TAG is …