The role of the serotonergic system at the interface of aggression and suicide

M Bortolato, N Pivac, DM Seler, MN Perkovic, M Pessia… - Neuroscience, 2013 - Elsevier
Alterations in serotonin (5-HT) neurochemistry have been implicated in the aetiology of all
major neuropsychiatric disorders, ranging from schizophrenia to mood and anxiety-spectrum …

Advances in tryptophan hydroxylase‐2 gene expression regulation: New insights into serotonin–stress interaction and clinical implications

GL Chen, GM Miller - … Journal of Medical Genetics Part B …, 2012 - Wiley Online Library
Abstract Serotonin (5‐HT) modulates the stress response by interacting with the hormonal
hypothalamic–pituitary–adrenal (HPA) axis and neuronal sympathetic nervous system …

Alcohol and the Brain–Gut Axis: The Involvement of Microglia and Enteric Glia in the Process of Neuro-Enteric Inflammation

MAS Khan, SL Chang - Cells, 2023 - mdpi.com
Binge or chronic alcohol consumption causes neuroinflammation and leads to alcohol use
disorder (AUD). AUD not only affects the central nervous system (CNS) but also leads to …

Effects of a variable light intensity lighting program on the welfare and performance of commercial broiler chickens

SW Kang, KD Christensen, MT Kidd Jr… - Frontiers in …, 2023 - frontiersin.org
Our previous variable-light intensity lighting program studies indicate the light intensity
preference behavior of broilers for their daily activity including eating and resting. To …

Degeneration of serotonin neurons triggers spasticity in amyotrophic lateral sclerosis

H El Oussini, J Scekic‐Zahirovic… - Annals of …, 2017 - Wiley Online Library
Objective Spasticity occurs in a wide range of neurological diseases, including
neurodegenerative diseases, after trauma, and after stroke, and is characterized by …

[HTML][HTML] Cannabinoid type-1 receptor signaling in central serotonergic neurons regulates anxiety-like behavior and sociability

M Häring, V Enk, A Aparisi Rey, S Loch… - Frontiers in Behavioral …, 2015 - frontiersin.org
The endocannabinoid (eCB) system possesses neuromodulatory functions by influencing
the release of various neurotransmitters, including γ-aminobutyric acid (GABA) and …

[6]-Gingerol Ameliorates Cisplatin-Induced Pica by Regulating the TPH/MAO-A/SERT/5-HT/5-HT3 Receptor System in Rats

Q Cheng, X Feng, Q Meng, Y Li, S Chen… - Drug Design …, 2020 - Taylor & Francis
Purpose [6]-gingerol is a bioactive compound extracted from ginger, a traditional anti-emetic
herb in Chinese medicine. Previous studies have demonstrated that [6]-gingerol can …

Serotonergic genes in the development of anxiety/depression-like state and pathology of aggressive behavior in male mice: RNA-seq data

NN Kudryavtseva, DA Smagin, IL Kovalenko… - Molecular biology, 2017 - Springer
In course of daily agonistic interactions, mice tend to stratify into those with chronic social
defeats and those that repeatedly display aggression, which lead to the development of …

1,25(OH)2D3 attenuates sleep disturbance in mouse models of Lewis lung cancer, in silico and in vivo

M Ai, S Li, H Chen, X Wang, J Sun… - Journal of Cellular …, 2021 - Wiley Online Library
Many clinical studies have reported that patients diagnosed with cancer will suffer from
sleep disturbance during their clinical process, especially among lung cancer patients, and …

Nice guys: Homozygocity for the TPH2-703G/T (rs4570625) minor allele promotes low aggressiveness and low anxiety

K Laas, E Kiive, J Mäestu, M Vaht, T Veidebaum… - Journal of Affective …, 2017 - Elsevier
Background Tryptophan hydroxylase (TPH) is the rate-limiting enzyme in the synthesis of
serotonin. We examined whether the TPH2 polymorphism-703G/T (rs4570625) is …