Nucleotide metabolism: a pan-cancer metabolic dependency
Metabolic alterations are a key hallmark of cancer cells, and the augmented synthesis and
use of nucleotide triphosphates is a critical and universal metabolic dependency of cancer …
use of nucleotide triphosphates is a critical and universal metabolic dependency of cancer …
[HTML][HTML] Mitochondrial complex I ROS production and redox signaling in hypoxia
CN Okoye, SA Koren, AP Wojtovich - Redox biology, 2023 - Elsevier
Mitochondria are a main source of cellular energy. Oxidative phosphorylation (OXPHOS) is
the major process of aerobic respiration. Enzyme complexes of the electron transport chain …
the major process of aerobic respiration. Enzyme complexes of the electron transport chain …
Mitochondria as playmakers of apoptosis, autophagy and senescence
Mitochondria are the key energy-producing organelles and cellular source of reactive
species. They are responsible for managing cell life and death by a balanced homeostasis …
species. They are responsible for managing cell life and death by a balanced homeostasis …
Oxygen battle in the gut: Hypoxia and hypoxia-inducible factors in metabolic and inflammatory responses in the intestine
The gastrointestinal tract is a highly proliferative and regenerative tissue. The intestine also
harbors a large and diverse microbial population collectively called the gut microbiome …
harbors a large and diverse microbial population collectively called the gut microbiome …
Large Stokes shift benzothiazolium cyanine dyes with improved intramolecular charge transfer (ICT) for cell imaging applications
CS Abeywickrama - Chemical Communications, 2022 - pubs.rsc.org
Intramolecular Charge Transfer (ICT) is a crucial photophysical phenomenon that can be
used to improve the Stokes' shift in fluorescent dyes. The introduction of molecular …
used to improve the Stokes' shift in fluorescent dyes. The introduction of molecular …
Mitochondria, bioenergetics and apoptosis in cancer
PJ Burke - Trends in cancer, 2017 - cell.com
Until recently, the dual roles of mitochondria in ATP production (bioenergetics) and
apoptosis (cell life/death decision) were thought to be separate. New evidence points to a …
apoptosis (cell life/death decision) were thought to be separate. New evidence points to a …
Mitochondrial biogenesis and metabolic hyperactivation limits the application of MTT assay in the estimation of radiation induced growth inhibition
Metabolic viability based high throughput assays like MTT and MTS are widely used in
assessing the cell viability. However, alteration in both mitochondrial content and …
assessing the cell viability. However, alteration in both mitochondrial content and …
The roles of reactive oxygen species and antioxidants in cryopreservation
Cryopreservation has facilitated advancement of biological research by allowing the storage
of cells over prolonged periods of time. While cryopreservation at extremely low …
of cells over prolonged periods of time. While cryopreservation at extremely low …
Zinc oxide nanoparticles induce apoptosis and autophagy in human ovarian cancer cells
DP Bai, XF Zhang, GL Zhang, YF Huang… - International journal …, 2017 - Taylor & Francis
Background Zinc oxide nanoparticles (ZnO NPs) are frequently used in industrial products
such as paint, surface coating, and cosmetics, and recently, they have been explored in …
such as paint, surface coating, and cosmetics, and recently, they have been explored in …
A photostable AIE luminogen for specific mitochondrial imaging and tracking
Tracking the dynamics of mitochondrial morphology has attracted much research interest
because of its involvement in early stage apoptosis and degenerative conditions. To follow …
because of its involvement in early stage apoptosis and degenerative conditions. To follow …