[HTML][HTML] Understanding the complex genetics and molecular mechanisms underlying glaucoma
W Wang, H Wang - Molecular Aspects of Medicine, 2023 - Elsevier
Glaucoma is the leading cause of irreversible blindness worldwide. Currently the only
effective treatment for glaucoma is to reduce the intraocular pressure, which can halt the …
effective treatment for glaucoma is to reduce the intraocular pressure, which can halt the …
Genetic association of lipid traits and lipid-related drug targets with normal tension glaucoma: a Mendelian randomization study for predictive preventive and …
T Kang, Y Zhou, C Fan, Y Zhang, Y Yang, J Jiang - EPMA Journal, 2024 - Springer
Background Glaucoma is the leading cause of irreversible blindness worldwide. Normal
tension glaucoma (NTG) is a distinct subtype characterized by intraocular pressures (IOP) …
tension glaucoma (NTG) is a distinct subtype characterized by intraocular pressures (IOP) …
Denoising OCT videos based on temporal redundancy
The identification of eye diseases and their progression often relies on a clear visualization
of the anatomy and on different metrics extracted from Optical Coherence Tomography …
of the anatomy and on different metrics extracted from Optical Coherence Tomography …
Biomechanical Strain Responses in the Optic Nerve Head Region in Glaucoma Patients After Intraocular Pressure Lowering
Z Yuan, CA Czerpak, MS Kashaf, HA Quigley… - medRxiv, 2023 - medrxiv.org
Objective To measure strain values and their association with intraocular pressure (IOP)
change across five posterior eye regions in glaucoma patients. Design Cohort study …
change across five posterior eye regions in glaucoma patients. Design Cohort study …
Biomechanics-Function in Glaucoma: Improved Visual Field Predictions from IOP-Induced Neural Strains
Purpose (1) To assess whether neural tissue structure and biomechanics could predict
functional loss in glaucoma;(2) To evaluate the importance of biomechanics in making such …
functional loss in glaucoma;(2) To evaluate the importance of biomechanics in making such …
Reverse translation of artificial intelligence in glaucoma: Connecting basic science with clinical applications
Artificial intelligence (AI) has been approved for biomedical research in diverse areas from
bedside clinical studies to benchtop basic scientific research. For ophthalmic research, in …
bedside clinical studies to benchtop basic scientific research. For ophthalmic research, in …
Adduction induces large optic nerve head deformations in subjects with normal-tension glaucoma
Purpose To assess intraocular pressure (IOP)-induced and gaze-induced optic nerve head
(ONH) strains in subjects with high-tension glaucoma (HTG) and normal-tension glaucoma …
(ONH) strains in subjects with high-tension glaucoma (HTG) and normal-tension glaucoma …
[HTML][HTML] A Noninvasive Clinical Method to Measure in Vivo Mechanical Strains of the Lamina Cribrosa by OCT
V Hannay, C Czerpak, HA Quigley, TD Nguyen - Ophthalmology Science, 2024 - Elsevier
Objective To measure mechanical strain of the lamina cribrosa (LC) after intraocular
pressure (IOP) change produced 1 week after a change in glaucoma medication. Design …
pressure (IOP) change produced 1 week after a change in glaucoma medication. Design …
AI-based clinical assessment of optic nerve head robustness superseding biomechanical testing
Background/aims To use artificial intelligence (AI) to:(1) exploit biomechanical knowledge of
the optic nerve head (ONH) from a relatively large population;(2) assess ONH robustness …
the optic nerve head (ONH) from a relatively large population;(2) assess ONH robustness …
Lamina Cribrosa Morphology in Normal Tension Glaucoma According to the Location of Visual Field Defects
YS Kang, Z Haowei, MS Sung, SW Park - Journal of Glaucoma, 2023 - journals.lww.com
Purpose: The aim of this study was to investigate morphologic differences in the LC in
normal tension glaucoma (NTG) according to the location of VF defects. Design: This study …
normal tension glaucoma (NTG) according to the location of VF defects. Design: This study …