Risk factors for delirium and cognitive decline following coronary artery bypass grafting surgery: a systematic review and meta‐analysis

D Greaves, PJ Psaltis, DHJ Davis, TJ Ross… - Journal of the …, 2020 - Am Heart Assoc
Background Coronary artery bypass grafting (CABG) is known to improve heart function and
quality of life, while rates of surgery‐related mortality are low. However, delirium and …

Effect of dexmedetomidine on postoperative cognitive dysfunction and inflammation in patients after general anaesthesia: A PRISMA-compliant systematic review and …

W Yang, LS Kong, XX Zhu, RX Wang, Y Liu, LR Chen - Medicine, 2019 - journals.lww.com
Background: Neuroprotective effects of dexmedetomidine are reported in preclinical and
clinical studies but evidence regarding the postoperative neurocognitive function is still …

Perioperative electroencephalogram spectral dynamics related to postoperative delirium in older patients

S Koch, V Windmann, S Chakravarty… - Anesthesia & …, 2021 - journals.lww.com
BACKGROUND: Intraoperative electroencephalography (EEG) signatures related to the
development of postoperative delirium (POD) in older patients are frequently studied …

Associations of the metabolic syndrome and its components with cognitive impairment in older adults

I Feinkohl, J Janke, D Hadzidiakos, A Slooter… - BMC geriatrics, 2019 - Springer
Abstract Background The metabolic syndrome (MetS) is an established cardiovascular risk
factor. Here, we investigated its role in cognitive impairment. Methods Baseline data from …

Biomarkers and postoperative cognitive function: could it be that easy?

ST Schaefer, S Koenigsperger, C Olotu… - Current Opinion in …, 2019 - journals.lww.com
Single markers for postoperative cognitive impairment cannot predict POD/POCD in geriatric
patients. However, a wisely arranged battery of promising biomarkers might achieve a …

[HTML][HTML] The association between brain volume, cortical brain infarcts, and physical frailty

IMJ Kant, J de Bresser, SJT van Montfort, E Aarts… - Neurobiology of …, 2018 - Elsevier
Physical frailty is an age-associated syndrome of decreased reserve leading to vulnerability
to physiological stressors and associated with negative outcomes. The underlying structural …

The correlation of intraoperative hypotension and postoperative cognitive impairment: a meta-analysis of randomized controlled trials

X Feng, J Hu, F Hua, J Zhang, L Zhang, G Xu - BMC anesthesiology, 2020 - Springer
Background There is no consensus on whether intraoperative hypotension is associated
with postoperative cognitive impairment. Hence, we performed a meta-analysis to evaluate …

The association between frailty and MRI features of cerebral small vessel disease

IMJ Kant, HJMM Mutsaerts, SJT van Montfort… - Scientific reports, 2019 - nature.com
Frailty is a common syndrome in older individuals that is associated with poor cognitive
outcome. The underlying brain correlates of frailty are unclear. The aim of this study was to …

[HTML][HTML] Functional brain network and trail making test changes following major surgery and postoperative delirium: a prospective, multicentre, observational cohort …

FL Ditzel, SJT van Montfort, LM Vernooij… - British Journal of …, 2023 - Elsevier
Background Delirium is a frequent complication after surgery in older adults and is
associated with an increased risk of long-term cognitive impairment and dementia …

[HTML][HTML] Metabolic syndrome and the risk of postoperative delirium and postoperative cognitive dysfunction: a multi-centre cohort study

I Feinkohl, J Janke, AJC Slooter, G Winterer… - British Journal of …, 2023 - Elsevier
Background Metabolic syndrome and its components are risk factors for cognitive
impairment, but their contribution to perioperative neurocognitive disorders is unknown. We …