Background Denosumab, an anti-resorptive agent, IgG2 monoclonal antibody for human
Receptor activator of nuclear factor-kappa B ligand (RANKL), has been related to the …

A retrospective analysis was performed with the aim of understanding whether the risk
factors showed in the literature for medication-related osteonecrosis of the jaws (MRONJ) in …

Medication-related osteonecrosis of the jaw (MRONJ) is a rare, but devastating condition
caused by bisphosphonates, RANKL inhibitors, anti-angiogenic medications, and DMARDs …

Alternative therapies associating natural products and nanobiotechnology show new
perspectives on controlled drug release. In this context, nanoemulsions (NEs) present …

Purpose To evaluate the effect of repeated administration of zoledronic acid (ZA) on the
development and severity of osteonecrosis of the jaws. Methods In the experiment, 36 rats …

New surgical techniques using narrow, tilted implants positioned through a magneto-
dynamic tool in guided surgery for a Toronto restoration. A 69-year-old woman wanted fixed …

We investigated the possibilities of angioprotection and the reduction of osteonecrosis in
rats that had been given bisphosphonates. In our experiment, 27 rats were divided into three …

The association of the high blood pressure D variant of the angiotensin-converting enzyme
(ACE) gene with medication-related jaw osteonecrosis (MRONJ) is described in two Greek …

Introduction: The use of bisphosphonates in treatment of osteoporosis declined significantly
over the past decade. There is currently great concern, among patients and physicians …

Objetivo: Identificar a prevalência e os possíveis fatores de risco para o desenvolvimento de
osteonecrose em pacientes tratados com bifosfonatos no HUCAM/UFES. Métodos: Foram …