[HTML][HTML] Mechanistic analysis by NMR spectroscopy: A users guide

Y Ben-Tal, PJ Boaler, HJA Dale, RE Dooley… - Progress in nuclear …, 2022 - Elsevier
A 'principles and practice'tutorial-style review of the application of solution-phase NMR in the
analysis of the mechanisms of homogeneous organic and organometallic reactions and …

Parahydrogen‐based hyperpolarization for biomedicine

JB Hövener, AN Pravdivtsev, B Kidd… - Angewandte Chemie …, 2018 - Wiley Online Library
Magnetic resonance (MR) is one of the most versatile and useful physical effects used for
human imaging, chemical analysis, and the elucidation of molecular structures. However, its …

Hyperpolarized NMR Spectroscopy: d‐DNP, PHIP, and SABRE Techniques

KV Kovtunov, EV Pokochueva… - Chemistry–An Asian …, 2018 - Wiley Online Library
The intensity of NMR signals can be enhanced by several orders of magnitude by using
various techniques for the hyperpolarization of different molecules. Such approaches can …

Facing and overcoming sensitivity challenges in biomolecular NMR spectroscopy

JH Ardenkjaer‐Larsen, GS Boebinger… - Angewandte Chemie …, 2015 - Wiley Online Library
In the Spring of 2013, NMR spectroscopists convened at the Weizmann Institute in Israel to
brainstorm on approaches to improve the sensitivity of NMR experiments, particularly when …

NMR hyperpolarization techniques for biomedicine

P Nikolaou, BM Goodson… - Chemistry–A European …, 2015 - Wiley Online Library
Recent developments in NMR hyperpolarization have enabled a wide array of new in vivo
molecular imaging modalities, ranging from functional imaging of the lungs to metabolic …

Catalyst-Free Aqueous Hyperpolarized [1-13C]Pyruvate Obtained by Re-Dissolution Signal Amplification by Reversible Exchange

AB Schmidt, H de Maissin, I Adelabu, S Nantogma… - ACS …, 2022 - ACS Publications
Despite great successes in oncology, patient outcomes are often still discouraging, and
hence the diagnostic imaging paradigm is increasingly shifting toward functional imaging of …

The theory and practice of hyperpolarization in magnetic resonance using parahydrogen

RA Green, RW Adams, SB Duckett, RE Mewis… - Progress in nuclear …, 2012 - Elsevier
NMR spectroscopy is arguably the most powerful and versatile analytical spectroscopic
method available to analyze nuclides which possess a magnetic dipole moment and …

Direct and cost-efficient hyperpolarization of long-lived nuclear spin states on universal 15N2-diazirine molecular tags

T Theis, GX Ortiz Jr, AWJ Logan, KE Claytor, Y Feng… - Science …, 2016 - science.org
Conventional magnetic resonance (MR) faces serious sensitivity limitations which can be
overcome by hyperpolarization methods, but the most common method (dynamic nuclear …

Instrumentation for hydrogenative parahydrogen-based hyperpolarization techniques

AB Schmidt, CR Bowers, K Buckenmaier… - Analytical …, 2022 - ACS Publications
The unique properties of the entangled, antisymmetric nuclear spin state of dihydrogen,
parahydrogen (pH2), has intrigued physicists, chemists, and other scientists for almost a …

15N Hyperpolarization by Reversible Exchange Using SABRE-SHEATH

ML Truong, T Theis, AM Coffey… - The journal of …, 2015 - ACS Publications
NMR signal amplification by reversible exchange (SABRE) is a NMR hyperpolarization
technique that enables nuclear spin polarization enhancement of molecules via concurrent …